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Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry.
Dixon T, MacPherson D, Mostofian B, Dauzhenka T, Lotz S, McGee D, Shechter S, Shrestha UR, Wiewiora R, McDargh ZA, Pei F, Pal R, Ribeiro JV, Wilkerson T, Sachdeva V, Gao N, Jain S, Sparks S, Li Y, Vinitsky A, Zhang X, Razavi AM, Kolossváry I, Imbriglio J, Evdokimov A, Bergeron L, Zhou W, Adhikari J, Ruprecht B, Dickson A, Xu H, Sherman W, Izaguirre JA. Dixon T, et al. Among authors: ruprecht b. Nat Commun. 2022 Oct 6;13(1):5884. doi: 10.1038/s41467-022-33575-4. Nat Commun. 2022. PMID: 36202813 Free PMC article.
A mass spectrometry-based proteome map of drug action in lung cancer cell lines.
Ruprecht B, Di Bernardo J, Wang Z, Mo X, Ursu O, Christopher M, Fernandez RB, Zheng L, Dill BD, Wang H, Xu Y, Liaw A, Mortison JD, Siriwardana N, Andresen B, Glick M, Tata JR, Kutilek V, Cornella-Taracido I, Chi A. Ruprecht B, et al. Nat Chem Biol. 2020 Oct;16(10):1111-1119. doi: 10.1038/s41589-020-0572-3. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690943
Proteome activity landscapes of tumor cell lines determine drug responses.
Frejno M, Meng C, Ruprecht B, Oellerich T, Scheich S, Kleigrewe K, Drecoll E, Samaras P, Hogrebe A, Helm D, Mergner J, Zecha J, Heinzlmeir S, Wilhelm M, Dorn J, Kvasnicka HM, Serve H, Weichert W, Kuster B. Frejno M, et al. Among authors: ruprecht b. Nat Commun. 2020 Jul 20;11(1):3639. doi: 10.1038/s41467-020-17336-9. Nat Commun. 2020. PMID: 32686665 Free PMC article.
A bead-based western for high-throughput cellular signal transduction analyses.
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, Joos TO, Kling S, Poetz O, Fehm T, Neubauer H, Kuster B, Templin MF. Treindl F, et al. Among authors: ruprecht b. Nat Commun. 2016 Sep 23;7:12852. doi: 10.1038/ncomms12852. Nat Commun. 2016. PMID: 27659302 Free PMC article.
49 results