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391 results

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Pegylated interferon-2α invokes graft-versus-leukemia effects in patients relapsing after allogeneic stem cell transplantation.
Henden AS, Varelias A, Leach J, Sturgeon E, Avery J, Kelly J, Olver S, Samson L, Hartel G, Durrant S, Butler J, Morton AJ, Misra A, Tey SK, Subramoniapillai E, Curley C, Kennedy G, Hill GR. Henden AS, et al. Among authors: samson l. Blood Adv. 2019 Oct 22;3(20):3013-3019. doi: 10.1182/bloodadvances.2019000453. Blood Adv. 2019. PMID: 31648324 Free PMC article. Clinical Trial.
CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant.
Yeh AC, Varelias A, Reddy A, Barone SM, Olver SD, Chilson K, Onstad LE, Ensbey KS, Henden AS, Samson L, Jaeger CA, Bi T, Dahlman KB, Kim TK, Zhang P, Degli-Esposti MA, Newell EW, Jagasia MH, Irish JM, Lee SJ, Hill GR. Yeh AC, et al. Among authors: samson l. Blood. 2021 Dec 30;138(26):2874-2885. doi: 10.1182/blood.2020009492. Blood. 2021. PMID: 34115118 Free PMC article.
Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT.
Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, Maruyama Y, Ishiyama K, Ichinohe T, Atsuta Y, Blazar BR, Furlan SN, Ogawa H, Hill GR. Inoue T, et al. Among authors: samson l. JCI Insight. 2021 Nov 22;6(22):e153551. doi: 10.1172/jci.insight.153551. JCI Insight. 2021. PMID: 34637399 Free PMC article.
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Minnie SA, Waltner OG, Ensbey KS, Nemychenkov NS, Schmidt CR, Bhise SS, Legg SRW, Campoy G, Samson LD, Kuns RD, Zhou T, Huck JD, Vuckovic S, Zamora D, Yeh A, Spencer A, Koyama M, Markey KA, Lane SW, Boeckh M, Ring AM, Furlan SN, Hill GR. Minnie SA, et al. Sci Immunol. 2022 Oct 21;7(76):eabo3420. doi: 10.1126/sciimmunol.abo3420. Epub 2022 Oct 14. Sci Immunol. 2022. PMID: 36240285 Free PMC article.
Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.
Zhang P, Lee JS, Gartlan KH, Schuster IS, Comerford I, Varelias A, Ullah MA, Vuckovic S, Koyama M, Kuns RD, Locke KR, Beckett KJ, Olver SD, Samson LD, Montes de Oca M, de Labastida Rivera F, Clouston AD, Belz GT, Blazar BR, MacDonald KP, McColl SR, Thomas R, Engwerda CR, Degli-Esposti MA, Kallies A, Tey SK, Hill GR. Zhang P, et al. Sci Immunol. 2017 Apr 7;2(10):eaah7152. doi: 10.1126/sciimmunol.aah7152. Sci Immunol. 2017. PMID: 28738016 Free PMC article.
Phase I Trial of Inducible Caspase 9 T Cells in Adult Stem Cell Transplant Demonstrates Massive Clonotypic Proliferative Potential and Long-term Persistence of Transgenic T Cells.
Zhang P, Raju J, Ullah MA, Au R, Varelias A, Gartlan KH, Olver SD, Samson LD, Sturgeon E, Zomerdijk N, Avery J, Gargett T, Brown MP, Coin LJ, Ganesamoorthy D, Hutchins C, Pratt GR, Kennedy GA, Morton AJ, Curley CI, Hill GR, Tey SK. Zhang P, et al. Clin Cancer Res. 2019 Mar 15;25(6):1749-1755. doi: 10.1158/1078-0432.CCR-18-3069. Epub 2019 Feb 14. Clin Cancer Res. 2019. PMID: 30765390 Clinical Trial.
391 results