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A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation.
Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D. Yanchus C, et al. Among authors: zhou l. Science. 2022 Oct 7;378(6615):68-78. doi: 10.1126/science.abj2890. Epub 2022 Oct 6. Science. 2022. PMID: 36201590 Free PMC article.
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Inoue S, Hao Z, Elia AJ, Cescon D, Zhou L, Silvester J, Snow B, Harris IS, Sasaki M, Li WY, Itsumi M, Yamamoto K, Ueda T, Dominguez-Brauer C, Gorrini C, Chio II, Haight J, You-Ten A, McCracken S, Wakeham A, Ghazarian D, Penn LJ, Melino G, Mak TW. Inoue S, et al. Among authors: zhou l. Genes Dev. 2013 May 15;27(10):1101-14. doi: 10.1101/gad.214577.113. Genes Dev. 2013. PMID: 23699408 Free PMC article.
TAp73 is required for spermatogenesis and the maintenance of male fertility.
Inoue S, Tomasini R, Rufini A, Elia AJ, Agostini M, Amelio I, Cescon D, Dinsdale D, Zhou L, Harris IS, Lac S, Silvester J, Li WY, Sasaki M, Haight J, Brüstle A, Wakeham A, McKerlie C, Jurisicova A, Melino G, Mak TW. Inoue S, et al. Among authors: zhou l. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1843-8. doi: 10.1073/pnas.1323416111. Epub 2014 Jan 21. Proc Natl Acad Sci U S A. 2014. PMID: 24449892 Free PMC article.
DJ-1, a novel regulator of the tumor suppressor PTEN.
Kim RH, Peters M, Jang Y, Shi W, Pintilie M, Fletcher GC, DeLuca C, Liepa J, Zhou L, Snow B, Binari RC, Manoukian AS, Bray MR, Liu FF, Tsao MS, Mak TW. Kim RH, et al. Among authors: zhou l. Cancer Cell. 2005 Mar;7(3):263-73. doi: 10.1016/j.ccr.2005.02.010. Cancer Cell. 2005. PMID: 15766664 Free article.
Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila.
Peters M, DeLuca C, Hirao A, Stambolic V, Potter J, Zhou L, Liepa J, Snow B, Arya S, Wong J, Bouchard D, Binari R, Manoukian AS, Mak TW. Peters M, et al. Among authors: zhou l. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11305-10. doi: 10.1073/pnas.172382899. Epub 2002 Aug 9. Proc Natl Acad Sci U S A. 2002. PMID: 12172011 Free PMC article.
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.
Carnes MU, Quach BC, Zhou L, Han S, Tao R, Mandal M, Deep-Soboslay A, Marks JA, Page GP, Maher BS, Jaffe AE, Won H, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Hancock DB. Carnes MU, et al. Among authors: zhou l. Neuropsychopharmacology. 2024 Jun 4. doi: 10.1038/s41386-024-01885-4. Online ahead of print. Neuropsychopharmacology. 2024. PMID: 38830989
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