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Page 1
Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia.
Al-Mass A, Poursharifi P, Peyot ML, Lussier R, Chenier I, Leung YH, Ghosh A, Oppong A, Possik E, Mugabo Y, Ahmad R, Sladek R, Murthy Madiraju SR, Al-Mulla F, Prentki M. Al-Mass A, et al. Among authors: sladek r. Mol Metab. 2022 Dec;66:101609. doi: 10.1016/j.molmet.2022.101609. Epub 2022 Oct 2. Mol Metab. 2022. PMID: 36198384 Free PMC article.
Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression.
Pepin É, Al-Mass A, Attané C, Zhang K, Lamontagne J, Lussier R, Madiraju SR, Joly E, Ruderman NB, Sladek R, Prentki M, Peyot ML. Pepin É, et al. Among authors: sladek r. PLoS One. 2016 Apr 4;11(4):e0153017. doi: 10.1371/journal.pone.0153017. eCollection 2016. PLoS One. 2016. PMID: 27043434 Free PMC article.
Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals.
Gauthier MS, Pérusse JR, Lavoie MÈ, Sladek R, Madiraju SR, Ruderman NB, Coulombe B, Prentki M, Rabasa-Lhoret R. Gauthier MS, et al. Among authors: sladek r. J Clin Endocrinol Metab. 2014 Dec;99(12):E2518-28. doi: 10.1210/jc.2014-1662. J Clin Endocrinol Metab. 2014. PMID: 25210878 Free PMC article.
Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells.
El-Assaad W, Joly E, Barbeau A, Sladek R, Buteau J, Maestre I, Pepin E, Zhao S, Iglesias J, Roche E, Prentki M. El-Assaad W, et al. Among authors: sladek r. Endocrinology. 2010 Jul;151(7):3061-73. doi: 10.1210/en.2009-1238. Epub 2010 May 5. Endocrinology. 2010. PMID: 20444946
A genome-wide association study identifies novel risk loci for type 2 diabetes.
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P. Sladek R, et al. Nature. 2007 Feb 22;445(7130):881-5. doi: 10.1038/nature05616. Epub 2007 Feb 11. Nature. 2007. PMID: 17293876
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, Järvelin MR, Laitinen J, Lauritzen T, Marre M, Mazur A, Meyre D, Montpetit A, Pisinger C, Posner B, Poulsen P, Pouta A, Prentki M, Ribel-Madsen R, Ruokonen A, Sandbaek A, Serre D, Tichet J, Vaxillaire M, Wojtaszewski JF, Vaag A, Hansen T, Polychronakos C, Pedersen O, Froguel P, Sladek R. Rung J, et al. Among authors: sladek r. Nat Genet. 2009 Oct;41(10):1110-5. doi: 10.1038/ng.443. Epub 2009 Sep 6. Nat Genet. 2009. PMID: 19734900
211 results