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Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia.
Al-Mass A, Poursharifi P, Peyot ML, Lussier R, Chenier I, Leung YH, Ghosh A, Oppong A, Possik E, Mugabo Y, Ahmad R, Sladek R, Murthy Madiraju SR, Al-Mulla F, Prentki M. Al-Mass A, et al. Among authors: poursharifi p. Mol Metab. 2022 Dec;66:101609. doi: 10.1016/j.molmet.2022.101609. Epub 2022 Oct 2. Mol Metab. 2022. PMID: 36198384 Free PMC article.
Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes.
Mugabo Y, Zhao S, Seifried A, Gezzar S, Al-Mass A, Zhang D, Lamontagne J, Attane C, Poursharifi P, Iglesias J, Joly E, Peyot ML, Gohla A, Madiraju SR, Prentki M. Mugabo Y, et al. Among authors: poursharifi p. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E430-9. doi: 10.1073/pnas.1514375113. Epub 2016 Jan 11. Proc Natl Acad Sci U S A. 2016. PMID: 26755581 Free PMC article.
α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.
Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, Madiraju SR, Prentki M. Zhao S, et al. Among authors: poursharifi p. Cell Rep. 2016 Mar 29;14(12):2872-88. doi: 10.1016/j.celrep.2016.02.076. Epub 2016 Mar 17. Cell Rep. 2016. PMID: 26997277 Free article.
A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice.
Attané C, Peyot ML, Lussier R, Poursharifi P, Zhao S, Zhang D, Morin J, Pineda M, Wang S, Dumortier O, Ruderman NB, Mitchell GA, Simons B, Madiraju SR, Joly E, Prentki M. Attané C, et al. Among authors: poursharifi p. Diabetologia. 2016 Dec;59(12):2654-2663. doi: 10.1007/s00125-016-4105-2. Epub 2016 Sep 27. Diabetologia. 2016. PMID: 27677764 Free PMC article.
Adipose ABHD6 regulates tolerance to cold and thermogenic programs.
Poursharifi P, Attané C, Mugabo Y, Al-Mass A, Ghosh A, Schmitt C, Zhao S, Guida J, Lussier R, Erb H, Chenier I, Peyot ML, Joly E, Noll C, Carpentier AC, Madiraju SRM, Prentki M. Poursharifi P, et al. JCI Insight. 2020 Dec 17;5(24):e140294. doi: 10.1172/jci.insight.140294. JCI Insight. 2020. PMID: 33201859 Free PMC article.
Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress.
Al-Mass A, Poursharifi P, Peyot ML, Lussier R, Levens EJ, Guida J, Mugabo Y, Possik E, Ahmad R, Al-Mulla F, Sladek R, Madiraju SRM, Prentki M. Al-Mass A, et al. Among authors: poursharifi p. Mol Metab. 2022 Jun;60:101471. doi: 10.1016/j.molmet.2022.101471. Epub 2022 Mar 7. Mol Metab. 2022. PMID: 35272070 Free PMC article.
ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice.
Poursharifi P, Schmitt C, Chenier I, Leung YH, Oppong AK, Bai Y, Klein LL, Al-Mass A, Lussier R, Abu-Farha M, Abubaker J, Al-Mulla F, Peyot ML, Madiraju SRM, Prentki M. Poursharifi P, et al. Mol Metab. 2023 Dec;78:101822. doi: 10.1016/j.molmet.2023.101822. Epub 2023 Oct 12. Mol Metab. 2023. PMID: 37838014 Free PMC article.
C5a receptor deficiency alters energy utilization and fat storage.
Roy C, Gupta A, Fisette A, Lapointe M, Poursharifi P, Richard D, Lu H, Lu B, Gerard N, Gerard C, Cianflone K. Roy C, et al. Among authors: poursharifi p. PLoS One. 2013 May 7;8(5):e62531. doi: 10.1371/journal.pone.0062531. Print 2013. PLoS One. 2013. PMID: 23667486 Free PMC article.
21 results