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HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans.
Ma Y, Joyce A, Brandenburg O, Saatchi F, Stevens C, Toffessi Tcheuyap V, Christie A, Do QN, Fatunde O, Macchiaroli A, Wong SC, Woolford L, Yousuf Q, Miyata J, Carrillo D, Onabolu O, McKenzie T, Mishra A, Hardy T, He W, Li D, Ivanishev A, Zhang Q, Pedrosa I, Kapur P, Schluep T, Kanner SB, Hamilton J, Brugarolas J. Ma Y, et al. Among authors: pedrosa i. Clin Cancer Res. 2022 Dec 15;28(24):5405-5418. doi: 10.1158/1078-0432.CCR-22-0963. Clin Cancer Res. 2022. PMID: 36190432 Free PMC article.
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis.
Wang SS, Gu YF, Wolff N, Stefanius K, Christie A, Dey A, Hammer RE, Xie XJ, Rakheja D, Pedrosa I, Carroll T, McKay RM, Kapur P, Brugarolas J. Wang SS, et al. Among authors: pedrosa i. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16538-43. doi: 10.1073/pnas.1414789111. Epub 2014 Oct 30. Proc Natl Acad Sci U S A. 2014. PMID: 25359211 Free PMC article.
Stereotactic radiation therapy of renal cancer inferior vena cava tumor thrombus.
Hannan R, Margulis V, Chun SG, Cannon N, Kim DW, Abdulrahman RE, Sagalowsky A, Pedrosa I, Choy H, Brugarolas J, Timmerman RD. Hannan R, et al. Among authors: pedrosa i. Cancer Biol Ther. 2015;16(5):657-61. doi: 10.1080/15384047.2015.1026506. Cancer Biol Ther. 2015. PMID: 25800036 Free PMC article.
Tumor Vascularity in Renal Masses: Correlation of Arterial Spin-Labeled and Dynamic Contrast-Enhanced Magnetic Resonance Imaging Assessments.
Zhang Y, Kapur P, Yuan Q, Xi Y, Carvo I, Signoretti S, Dimitrov I, Cadeddu JA, Margulis V, Muradyan N, Brugarolas J, Madhuranthakam AJ, Pedrosa I. Zhang Y, et al. Among authors: pedrosa i. Clin Genitourin Cancer. 2016 Feb;14(1):e25-36. doi: 10.1016/j.clgc.2015.08.007. Epub 2015 Aug 29. Clin Genitourin Cancer. 2016. PMID: 26422014 Free PMC article.
Intratumor Heterogeneity of Perfusion and Diffusion in Clear-Cell Renal Cell Carcinoma: Correlation With Tumor Cellularity.
Yuan Q, Kapur P, Zhang Y, Xi Y, Carvo I, Signoretti S, Dimitrov IE, Cadeddu JA, Margulis V, Brugarolas J, Madhuranthakam AJ, Pedrosa I. Yuan Q, et al. Among authors: pedrosa i. Clin Genitourin Cancer. 2016 Dec;14(6):e585-e594. doi: 10.1016/j.clgc.2016.04.007. Epub 2016 Apr 22. Clin Genitourin Cancer. 2016. PMID: 27209349 Free PMC article.
Targeting renal cell carcinoma with a HIF-2 antagonist.
Chen W, Hill H, Christie A, Kim MS, Holloman E, Pavia-Jimenez A, Homayoun F, Ma Y, Patel N, Yell P, Hao G, Yousuf Q, Joyce A, Pedrosa I, Geiger H, Zhang H, Chang J, Gardner KH, Bruick RK, Reeves C, Hwang TH, Courtney K, Frenkel E, Sun X, Zojwalla N, Wong T, Rizzi JP, Wallace EM, Josey JA, Xie Y, Xie XJ, Kapur P, McKay RM, Brugarolas J. Chen W, et al. Among authors: pedrosa i. Nature. 2016 Nov 3;539(7627):112-117. doi: 10.1038/nature19796. Epub 2016 Sep 5. Nature. 2016. PMID: 27595394 Free PMC article.
299 results