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Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.
Khanova E, Wu R, Wang W, Yan R, Chen Y, French SW, Llorente C, Pan SQ, Yang Q, Li Y, Lazaro R, Ansong C, Smith RD, Bataller R, Morgan T, Schnabl B, Tsukamoto H. Khanova E, et al. Among authors: pan sq. Hepatology. 2018 May;67(5):1737-1753. doi: 10.1002/hep.29645. Epub 2018 Feb 27. Hepatology. 2018. PMID: 29108122 Free PMC article.
Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles.
Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, Brenner D, Kisseleva T. Liu X, et al. Among authors: pan sq. Hepatol Commun. 2020 Feb 6;4(4):606-626. doi: 10.1002/hep4.1483. eCollection 2020 Apr. Hepatol Commun. 2020. PMID: 32258954 Free PMC article.
Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice.
Eguchi A, Yan R, Pan SQ, Wu R, Kim J, Chen Y, Ansong C, Smith RD, Tempaku M, Ohno-Machado L, Takei Y, Feldstein AE, Tsukamoto H. Eguchi A, et al. Among authors: pan sq. J Mol Med (Berl). 2020 Jul;98(7):1021-1034. doi: 10.1007/s00109-020-01926-7. Epub 2020 Jun 18. J Mol Med (Berl). 2020. PMID: 32556367 Free PMC article.
Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis.
Sinha S, Aizawa S, Nakano Y, Rialdi A, Choi HY, Shrestha R, Pan SQ, Chen Y, Li M, Kapelanski-Lamoureux A, Yochum G, Sher L, Monga SP, Lazaris A, Machida K, Karin M, Guccione E, Tsukamoto H. Sinha S, et al. Among authors: pan sq. Nat Commun. 2023 May 8;14(1):2651. doi: 10.1038/s41467-023-38406-8. Nat Commun. 2023. PMID: 37156770 Free PMC article.
63 results