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TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. Watanabe M, et al. Among authors: novitch bg. Stem Cell Reports. 2022 Oct 11;17(10):2220-2238. doi: 10.1016/j.stemcr.2022.08.013. Epub 2022 Sep 29. Stem Cell Reports. 2022. PMID: 36179695 Free PMC article.
Neuronal organization: unsticking the cadherin code.
Pearson CA, Butler SJ, Novitch BG. Pearson CA, et al. Among authors: novitch bg. Curr Biol. 2014 Dec 1;24(23):R1127-9. doi: 10.1016/j.cub.2014.10.034. Epub 2014 Dec 1. Curr Biol. 2014. PMID: 25465332 Free article.
Cbx3 maintains lineage specificity during neural differentiation.
Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. Huang C, et al. Among authors: novitch bg. Genes Dev. 2017 Feb 1;31(3):241-246. doi: 10.1101/gad.292169.116. Genes Dev. 2017. PMID: 28270516 Free PMC article.
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.
Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, Zhao H, Li L, Vishlaghi N, Buth JE, Au C, Liu Y, Lu N, Du P, Qin FX, Zhang B, Gong D, Dai X, Sun R, Novitch BG, Xu Z, Qin CF, Cheng G. Li C, et al. Among authors: novitch bg. Immunity. 2017 Mar 21;46(3):446-456. doi: 10.1016/j.immuni.2017.02.012. Epub 2017 Mar 14. Immunity. 2017. PMID: 28314593 Free PMC article.
Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.
Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. Watanabe M, et al. Among authors: novitch bg. Cell Rep. 2017 Oct 10;21(2):517-532. doi: 10.1016/j.celrep.2017.09.047. Cell Rep. 2017. PMID: 29020636 Free PMC article.
Identification of neural oscillations and epileptiform changes in human brain organoids.
Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. Samarasinghe RA, et al. Among authors: novitch bg. Nat Neurosci. 2021 Oct;24(10):1488-1500. doi: 10.1038/s41593-021-00906-5. Epub 2021 Aug 23. Nat Neurosci. 2021. PMID: 34426698 Free PMC article.
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