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Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.
J Med Chem. 2022 Oct 13;65(19):13052-13073. doi: 10.1021/acs.jmedchem.2c00893. Epub 2022 Sep 30.
J Med Chem. 2022.
PMID: 36178776
Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012.
Galley G, Stalder H, Goergler A, Hoener MC, Norcross RD.
Galley G, et al. Among authors: goergler a.
Bioorg Med Chem Lett. 2012 Aug 15;22(16):5244-8. doi: 10.1016/j.bmcl.2012.06.060. Epub 2012 Jun 23.
Bioorg Med Chem Lett. 2012.
PMID: 22795332
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Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists.
Galley G, Beurier A, Décoret G, Goergler A, Hutter R, Mohr S, Pähler A, Schmid P, Türck D, Unger R, Zbinden KG, Hoener MC, Norcross RD.
Galley G, et al. Among authors: goergler a.
ACS Med Chem Lett. 2015 Dec 30;7(2):192-7. doi: 10.1021/acsmedchemlett.5b00449. eCollection 2016 Feb 11.
ACS Med Chem Lett. 2015.
PMID: 26985297
Free PMC article.
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