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Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR, Ostrander EL, Kukhar O, Mallaney C, Sun J, Haussler E, Celik H, Koh WK, King KY, Gontarz P, Challen GA. Zhang CR, et al. Among authors: challen ga. Blood Cancer Discov. 2022 May 5;3(3):220-239. doi: 10.1158/2643-3230.BCD-21-0132. Blood Cancer Discov. 2022. PMID: 35394496 Free PMC article.
Spatial Mapping of Hematopoietic Clones in Human Bone Marrow.
Young AL, Davis HC, Cox MJ, Parsons TM, Burkart SC, Bender DE, Sun L, Oh ST, Challen GA. Young AL, et al. Among authors: challen ga. Blood Cancer Discov. 2024 May 1;5(3):153-163. doi: 10.1158/2643-3230.BCD-23-0110. Blood Cancer Discov. 2024. PMID: 38421682
LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, Younger ST, Hoffman R, Gangat N, Ntziachristos P, Chandel NS, Levine RL, Rampal RK, Challen GA, Tefferi A, Crispino JD. Marinaccio C, et al. Among authors: challen ga. Cancer Discov. 2021 Jun;11(6):1398-1410. doi: 10.1158/2159-8290.CD-20-1353. Epub 2021 Feb 12. Cancer Discov. 2021. PMID: 33579786 Free PMC article.
DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Gottgens B, Lee JS, Rau R, Li W, Goodell MA. Yang L, et al. Among authors: challen ga. Cancer Cell. 2016 Jun 13;29(6):922-934. doi: 10.1016/j.ccell.2016.05.003. Cancer Cell. 2016. PMID: 27300438 Free PMC article.
62 results