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IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations.
Yang RR, Shi ZF, Zhang ZY, Chan AK, Aibaidula A, Wang WW, Kwan JSH, Poon WS, Chen H, Li WC, Chung NY, Punchhi G, Chu WC, Chan IS, Liu XZ, Mao Y, Li KK, Ng HK. Yang RR, et al. Among authors: chen h. Brain Pathol. 2020 May;30(3):541-553. doi: 10.1111/bpa.12801. Epub 2019 Dec 3. Brain Pathol. 2020. PMID: 31733156 Free PMC article.
Molecular landscape of IDH-wild type, pTERT-wild type adult glioblastomas.
Liu EM, Shi ZF, Li KK, Malta TM, Chung NY, Chen H, Chan JY, Poon MF, Kwan JS, Chan DT, Noushmehr H, Mao Y, Ng HK. Liu EM, et al. Among authors: chen h. Brain Pathol. 2022 Nov;32(6):e13107. doi: 10.1111/bpa.13107. Epub 2022 Jul 11. Brain Pathol. 2022. PMID: 35815721 Free PMC article.
Biomarker-based prognostic stratification of young adult glioblastoma.
Zhang RQ, Shi Z, Chen H, Chung NY, Yin Z, Li KK, Chan DT, Poon WS, Wu J, Zhou L, Chan AK, Mao Y, Ng HK. Zhang RQ, et al. Among authors: chen h. Oncotarget. 2016 Jan 26;7(4):5030-41. doi: 10.18632/oncotarget.5456. Oncotarget. 2016. PMID: 26452024 Free PMC article.
Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.
Li YX, Shi Z, Aibaidula A, Chen H, Tang Q, Li KK, Chung NY, Chan DT, Poon WS, Mao Y, Wu J, Zhou L, Chan AK, Ng HK. Li YX, et al. Among authors: chen h. Oncotarget. 2016 Oct 4;7(40):64615-64630. doi: 10.18632/oncotarget.11378. Oncotarget. 2016. PMID: 27556304 Free PMC article.
Adult IDH wild-type lower-grade gliomas should be further stratified.
Aibaidula A, Chan AK, Shi Z, Li Y, Zhang R, Yang R, Li KK, Chung NY, Yao Y, Zhou L, Wu J, Chen H, Ng HK. Aibaidula A, et al. Among authors: chen h. Neuro Oncol. 2017 Oct 1;19(10):1327-1337. doi: 10.1093/neuonc/nox078. Neuro Oncol. 2017. PMID: 28575485 Free PMC article.
Pediatric low-grade gliomas can be molecularly stratified for risk.
Yang RR, Aibaidula A, Wang WW, Chan AK, Shi ZF, Zhang ZY, Chan DTM, Poon WS, Liu XZ, Li WC, Zhang RQ, Li YX, Chung NY, Chen H, Wu J, Zhou L, Li KK, Ng HK. Yang RR, et al. Among authors: chen h. Acta Neuropathol. 2018 Oct;136(4):641-655. doi: 10.1007/s00401-018-1874-3. Epub 2018 Jun 14. Acta Neuropathol. 2018. PMID: 29948154
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