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Synthesis and biological evaluation of 2-methyl-1H-benzimidazole-5-carbohydrazides derivatives as modifiers of redox homeostasis of Trypanosoma cruzi.
Melchor-Doncel de la Torre S, Vázquez C, González-Chávez Z, Yépez-Mulia L, Nieto-Meneses R, Jasso-Chávez R, Saavedra E, Hernández-Luis F. Melchor-Doncel de la Torre S, et al. Among authors: vazquez c. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3403-3407. doi: 10.1016/j.bmcl.2017.06.013. Epub 2017 Jun 12. Bioorg Med Chem Lett. 2017. PMID: 28648464
Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.
González-Chávez Z, Vázquez C, Mejia-Tlachi M, Márquez-Dueñas C, Manning-Cela R, Encalada R, Rodríguez-Enríquez S, Michels PAM, Moreno-Sánchez R, Saavedra E. González-Chávez Z, et al. Among authors: vazquez c. Redox Biol. 2019 Sep;26:101231. doi: 10.1016/j.redox.2019.101231. Epub 2019 May 28. Redox Biol. 2019. PMID: 31203195 Free PMC article.
Computational Drug Repositioning for Chagas Disease Using Protein-Ligand Interaction Profiling.
Juárez-Saldivar A, Schroeder M, Salentin S, Haupt VJ, Saavedra E, Vázquez C, Reyes-Espinosa F, Herrera-Mayorga V, Villalobos-Rocha JC, García-Pérez CA, Campillo NE, Rivera G. Juárez-Saldivar A, et al. Among authors: vazquez c. Int J Mol Sci. 2020 Jun 16;21(12):4270. doi: 10.3390/ijms21124270. Int J Mol Sci. 2020. PMID: 32560043 Free PMC article.
917 results