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Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
Peterson AA, Rangwala AM, Thakur MK, Ward PS, Hung C, Outhwaite IR, Chan AI, Usanov DL, Mootha VK, Seeliger MA, Liu DR. Peterson AA, et al. Among authors: seeliger ma. Nat Chem Biol. 2022 Nov;18(11):1184-1195. doi: 10.1038/s41589-022-01116-1. Epub 2022 Sep 26. Nat Chem Biol. 2022. PMID: 36163383 Free PMC article.
Kinase inhibitors: an allosteric add-on.
Foda ZH, Seeliger MA. Foda ZH, et al. Among authors: seeliger ma. Nat Chem Biol. 2014 Oct;10(10):796-7. doi: 10.1038/nchembio.1630. Epub 2014 Sep 7. Nat Chem Biol. 2014. PMID: 25195010 No abstract available.
What Makes a Kinase Promiscuous for Inhibitors?
Hanson SM, Georghiou G, Thakur MK, Miller WT, Rest JS, Chodera JD, Seeliger MA. Hanson SM, et al. Among authors: seeliger ma. Cell Chem Biol. 2019 Mar 21;26(3):390-399.e5. doi: 10.1016/j.chembiol.2018.11.005. Epub 2019 Jan 3. Cell Chem Biol. 2019. PMID: 30612951 Free PMC article.
Resistance to kinase inhibition through shortened target engagement.
Rangwala AM, Berger BT, Robers MB, Knapp S, Seeliger MA. Rangwala AM, et al. Among authors: seeliger ma. Mol Cell Oncol. 2022 Jan 22;9(1):2029999. doi: 10.1080/23723556.2022.2029999. eCollection 2022. Mol Cell Oncol. 2022. PMID: 35252553 Free PMC article.
76 results