Chan AI - Search Results

1

Discovery and molecular basis of subtype-selective cyclophilin inhibitors.

Peterson AA, Rangwala AM, Thakur MK, Ward PS, Hung C, Outhwaite IR, Chan AI, Usanov DL, Mootha VK, Seeliger MA, Liu DR. Peterson AA, et al. Among authors: chan ai. Nat Chem Biol. 2022 Nov;18(11):1184-1195. doi: 10.1038/s41589-022-01116-1. Epub 2022 Sep 26. Nat Chem Biol. 2022. PMID: 36163383 Free PMC article.

2

Novel selection methods for DNA-encoded chemical libraries.

Chan AI, McGregor LM, Liu DR. Chan AI, et al. Curr Opin Chem Biol. 2015 Jun;26:55-61. doi: 10.1016/j.cbpa.2015.02.010. Epub 2015 Feb 24. Curr Opin Chem Biol. 2015. PMID: 25723146 Free PMC article. Review.

3

Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.

Aleem S, Georghiou G, Kleiner RE, Guja K, Craddock BP, Lyczek A, Chan AI, Garcia-Diaz M, Miller WT, Liu DR, Seeliger MA. Aleem S, et al. Among authors: chan ai. Cell Chem Biol. 2016 Sep 22;23(9):1103-1112. doi: 10.1016/j.chembiol.2016.07.017. Epub 2016 Sep 1. Cell Chem Biol. 2016. PMID: 27593110 Free PMC article.

4

Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection.

Chan AI, McGregor LM, Jain T, Liu DR. Chan AI, et al. J Am Chem Soc. 2017 Aug 2;139(30):10192-10195. doi: 10.1021/jacs.7b04880. Epub 2017 Jul 20. J Am Chem Soc. 2017. PMID: 28689404 Free PMC article.

5

Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules.

Usanov DL, Chan AI, Maianti JP, Liu DR. Usanov DL, et al. Among authors: chan ai. Nat Chem. 2018 Jul;10(7):704-714. doi: 10.1038/s41557-018-0033-8. Epub 2018 Apr 2. Nat Chem. 2018. PMID: 29610462 Free PMC article.

6

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1.

Harmand TJ, Bousbaine D, Chan A, Zhang X, Liu DR, Tam JP, Ploegh HL. Harmand TJ, et al. Bioconjug Chem. 2018 Oct 17;29(10):3245-3249. doi: 10.1021/acs.bioconjchem.8b00563. Epub 2018 Sep 21. Bioconjug Chem. 2018. PMID: 30231608 Free PMC article.

7

Author Correction: Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules.

Usanov DL, Chan AI, Maianti JP, Liu DR. Usanov DL, et al. Among authors: chan ai. Nat Chem. 2019 Nov;11(11):1067. doi: 10.1038/s41557-019-0360-4. Nat Chem. 2019. PMID: 31576016

8

Multimodal small-molecule screening for human prion protein binders.

Reidenbach AG, Mesleh MF, Casalena D, Vallabh SM, Dahlin JL, Leed AJ, Chan AI, Usanov DL, Yehl JB, Lemke CT, Campbell AJ, Shah RN, Shrestha OK, Sacher JR, Rangel VL, Moroco JA, Sathappa M, Nonato MC, Nguyen KT, Wright SK, Liu DR, Wagner FF, Kaushik VK, Auld DS, Schreiber SL, Minikel EV. Reidenbach AG, et al. Among authors: chan ai. J Biol Chem. 2020 Sep 25;295(39):13516-13531. doi: 10.1074/jbc.RA120.014905. Epub 2020 Jul 28. J Biol Chem. 2020. PMID: 32723867 Free PMC article.

9

Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries.

Chan AI, Sawant MS, Burdick DJ, Tom J, Song A, Cunningham CN. Chan AI, et al. ACS Chem Biol. 2023 Jan 20;18(1):81-90. doi: 10.1021/acschembio.2c00712. Epub 2023 Jan 6. ACS Chem Biol. 2023. PMID: 36607609 Free PMC article.

10

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening.

Cavett V, Chan AI, Cunningham CN, Paegel BM. Cavett V, et al. Among authors: chan ai. ACS Cent Sci. 2023 Jul 13;9(8):1603-1610. doi: 10.1021/acscentsci.3c00316. eCollection 2023 Aug 23. ACS Cent Sci. 2023. PMID: 37637732 Free PMC article.

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