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Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects.
Chatturong U, Martin H, Totoson P, Ingkaninan K, Temkitthawon P, Sermsenaphorn S, Somarin T, Konsue A, Gleeson MP, Demougeot C, Chootip K. Chatturong U, et al. Vascul Pharmacol. 2022 Dec;147:107111. doi: 10.1016/j.vph.2022.107111. Epub 2022 Sep 24. Vascul Pharmacol. 2022. PMID: 36162651
Dried mulberry fruit ameliorates cardiovascular and liver histopathological changes in high-fat diet-induced hyperlipidemic mice.
Chaiwong S, Chatturong U, Chanasong R, Deetud W, To-On K, Puntheeranurak S, Chulikorn E, Kajsongkram T, Raksanoh V, Chinda K, Limpeanchob N, Trisat K, Somran J, Nuengchamnong N, Prajumwong P, Chootip K. Chaiwong S, et al. Among authors: chatturong u. J Tradit Complement Med. 2021 Feb 12;11(4):356-368. doi: 10.1016/j.jtcme.2021.02.006. eCollection 2021 Jul. J Tradit Complement Med. 2021. PMID: 34195030 Free PMC article.
The new quinazoline derivative (N2-methyl-N4-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats.
Chatturong U, Chootip K, Martin H, Tournier-Nappey M, Ingkaninan K, Temkitthawon P, Sermsenaphorn S, Somarin T, Konsue A, Gleeson MP, Totoson P, Demougeot C. Chatturong U, et al. Eur J Pharmacol. 2023 Aug 15;953:175829. doi: 10.1016/j.ejphar.2023.175829. Epub 2023 Jun 10. Eur J Pharmacol. 2023. PMID: 37307938