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Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5.
Behrangi N, Heinig L, Frintrop L, Santrau E, Kurth J, Krause B, Atanasova D, Clarner T, Fragoulis A, Joksch M, Rudolf H, Meuth SG, Joost S, Kipp M. Behrangi N, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2204509119. doi: 10.1073/pnas.2204509119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161894 Free PMC article.
Immune signatures of prodromal multiple sclerosis in monozygotic twins.
Gerdes LA, Janoschka C, Eveslage M, Mannig B, Wirth T, Schulte-Mecklenbeck A, Lauks S, Glau L, Gross CC, Tolosa E, Flierl-Hecht A, Ertl-Wagner B, Barkhof F, Meuth SG, Kümpfel T, Wiendl H, Hohlfeld R, Klotz L. Gerdes LA, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21546-21556. doi: 10.1073/pnas.2003339117. Epub 2020 Aug 17. Proc Natl Acad Sci U S A. 2020. PMID: 32817525 Free PMC article.
Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans.
Fleischer V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, Küry P, Gruchot J, Dietrich M, Hecker C, Müntefering T, Bock S, Oshaghi M, Radetz A, Cerina M, Krämer J, Wachsmuth L, Faber C, Lassmann H, Ruck T, Meuth SG, Muthuraman M, Groppa S. Fleischer V, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2025000118. doi: 10.1073/pnas.2025000118. Proc Natl Acad Sci U S A. 2021. PMID: 34479997 Free PMC article.
The trials and errors in MS therapy.
Kleinschnitz C, Meuth SG, Wiendl H. Kleinschnitz C, et al. Among authors: meuth sg. Int MS J. 2008 Sep;15(3):79-90. Int MS J. 2008. PMID: 18808741 Review.
Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.
Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, Hartwig M, Dornmair K, Hohlfeld R, Ziemssen T, Klotz L, Meuth SG, Wiendl H. Gross CC, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2973-82. doi: 10.1073/pnas.1524924113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162345 Free PMC article.
Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.
Göbel K, Asaridou CM, Merker M, Eichler S, Herrmann AM, Geuß E, Ruck T, Schüngel L, Groeneweg L, Narayanan V, Schneider-Hohendorf T, Gross CC, Wiendl H, Kehrel BE, Kleinschnitz C, Meuth SG. Göbel K, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):271-276. doi: 10.1073/pnas.1810020116. Epub 2018 Dec 17. Proc Natl Acad Sci U S A. 2019. PMID: 30559188 Free PMC article.
The next-generation sphingosine-1 receptor modulator BAF312 (siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis.
Hundehege P, Cerina M, Eichler S, Thomas C, Herrmann AM, Göbel K, Müntefering T, Fernandez-Orth J, Bock S, Narayanan V, Budde T, Speckmann EJ, Wiendl H, Schubart A, Ruck T, Meuth SG. Hundehege P, et al. Among authors: meuth sg. Neural Regen Res. 2019 Nov;14(11):1950-1960. doi: 10.4103/1673-5374.259622. Neural Regen Res. 2019. PMID: 31290453 Free PMC article.
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
Ostkamp P, Salmen A, Pignolet B, Görlich D, Andlauer TFM, Schulte-Mecklenbeck A, Gonzalez-Escamilla G, Bucciarelli F, Gennero I, Breuer J, Antony G, Schneider-Hohendorf T, Mykicki N, Bayas A, Then Bergh F, Bittner S, Hartung HP, Friese MA, Linker RA, Luessi F, Lehmann-Horn K, Mühlau M, Paul F, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber F, Wildemann B, Zettl UK, Ziemann U, Müller-Myhsok B, Kümpfel T, Klotz L, Meuth SG, Zipp F, Hemmer B, Hohlfeld R, Brassat D, Gold R, Gross CC, Lukas C, Groppa S, Loser K, Wiendl H, Schwab N; German Competence Network Multiple Sclerosis (KKNMS) and the BIONAT Network. Ostkamp P, et al. Among authors: meuth sg. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2018457118. doi: 10.1073/pnas.2018457118. Proc Natl Acad Sci U S A. 2021. PMID: 33376202 Free PMC article.
613 results