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c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis.
Vollmuth N, Schlicker L, Guo Y, Hovhannisyan P, Janaki-Raman S, Kurmasheva N, Schmitz W, Schulze A, Stelzner K, Rajeeve K, Rudel T. Vollmuth N, et al. Among authors: schulze a. Elife. 2022 Sep 26;11:e76721. doi: 10.7554/eLife.76721. Elife. 2022. PMID: 36155135 Free PMC article.
Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.
Bartmann C, Janaki Raman SR, Flöter J, Schulze A, Bahlke K, Willingstorfer J, Strunz M, Wöckel A, Klement RJ, Kapp M, Djuzenova CS, Otto C, Kämmerer U. Bartmann C, et al. Among authors: schulze a. Cancer Metab. 2018 Jun 11;6:8. doi: 10.1186/s40170-018-0180-9. eCollection 2018. Cancer Metab. 2018. PMID: 29942509 Free PMC article.
Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity.
Löffler MC, Mayer AE, Trujillo Viera J, Loza Valdes A, El-Merahbi R, Ade CP, Karwen T, Schmitz W, Slotta A, Erk M, Janaki-Raman S, Matesanz N, Torres JL, Marcos M, Sabio G, Eilers M, Schulze A, Sumara G. Löffler MC, et al. Among authors: schulze a. EMBO J. 2018 Nov 15;37(22):e99182. doi: 10.15252/embj.201899182. Epub 2018 Nov 2. EMBO J. 2018. PMID: 30389661 Free PMC article.
A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Schmidt S, Gay D, Uthe FW, Denk S, Paauwe M, Matthes N, Diefenbacher ME, Bryson S, Warrander FC, Erhard F, Ade CP, Baluapuri A, Walz S, Jackstadt R, Ford C, Vlachogiannis G, Valeri N, Otto C, Schülein-Völk C, Maurus K, Schmitz W, Knight JRP, Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A. Schmidt S, et al. Among authors: schulze a. Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685988 Free PMC article.
Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress.
Kaymak I, Maier CR, Schmitz W, Campbell AD, Dankworth B, Ade CP, Walz S, Paauwe M, Kalogirou C, Marouf H, Rosenfeldt MT, Gay DM, McGregor GH, Sansom OJ, Schulze A. Kaymak I, et al. Among authors: schulze a. Cancer Res. 2020 Jan 15;80(2):189-203. doi: 10.1158/0008-5472.CAN-19-0650. Epub 2019 Nov 19. Cancer Res. 2020. PMID: 31744820
902 results