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De novo design of buttressed loops for sculpting protein functions.
Jiang H, Jude KM, Wu K, Fallas J, Ueda G, Brunette TJ, Hicks DR, Pyles H, Yang A, Carter L, Lamb M, Li X, Levine PM, Stewart L, Garcia KC, Baker D. Jiang H, et al. Among authors: fallas j. Nat Chem Biol. 2024 May 30. doi: 10.1038/s41589-024-01632-2. Online ahead of print. Nat Chem Biol. 2024. PMID: 38816644
Computational design of non-porous pH-responsive antibody nanoparticles.
Yang EC, Divine R, Miranda MC, Borst AJ, Sheffler W, Zhang JZ, Decarreau J, Saragovi A, Abedi M, Goldbach N, Ahlrichs M, Dobbins C, Hand A, Cheng S, Lamb M, Levine PM, Chan S, Skotheim R, Fallas J, Ueda G, Lubner J, Somiya M, Khmelinskaia A, King NP, Baker D. Yang EC, et al. Among authors: fallas j. Nat Struct Mol Biol. 2024 May 9. doi: 10.1038/s41594-024-01288-5. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38724718
Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP. Ellis D, et al. Among authors: fallas ja. Cell Rep. 2023 Dec 26;42(12):113552. doi: 10.1016/j.celrep.2023.113552. Epub 2023 Dec 13. Cell Rep. 2023. PMID: 38096058 Free PMC article.
De novo design of buttressed loops for sculpting protein functions.
Jiang H, Jude KM, Wu K, Fallas J, Ueda G, Brunette TJ, Hicks D, Pyles H, Yang A, Carter L, Lamb M, Li X, Levine PM, Stewart L, Garcia KC, Baker D. Jiang H, et al. Among authors: fallas j. bioRxiv [Preprint]. 2023 Aug 23:2023.08.22.554384. doi: 10.1101/2023.08.22.554384. bioRxiv. 2023. PMID: 37662224 Free PMC article. Preprint.
Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP. Ellis D, et al. Among authors: fallas ja. bioRxiv [Preprint]. 2023 May 24:2023.05.23.541980. doi: 10.1101/2023.05.23.541980. bioRxiv. 2023. PMID: 37292995 Free PMC article. Updated. Preprint.
Computational design of non-porous, pH-responsive antibody nanoparticles.
Yang EC, Divine R, Miranda MC, Borst AJ, Sheffler W, Zhang JZ, Decarreau J, Saragovi A, Abedi M, Goldbach N, Ahlrichs M, Dobbins C, Hand A, Cheng S, Lamb M, Levine PM, Chan S, Skotheim R, Fallas J, Ueda G, Lubner J, Somiya M, Khmelinskaia A, King NP, Baker D. Yang EC, et al. Among authors: fallas j. bioRxiv [Preprint]. 2023 Apr 18:2023.04.17.537263. doi: 10.1101/2023.04.17.537263. bioRxiv. 2023. PMID: 37131615 Free PMC article. Updated. Preprint.
F-domain valency determines outcome of signaling through the angiopoietin pathway.
Zhao YT, Fallas JA, Saini S, Ueda G, Somasundaram L, Zhou Z, Xavier Raj I, Xu C, Carter L, Wrenn S, Mathieu J, Sellers DL, Baker D, Ruohola-Baker H. Zhao YT, et al. Among authors: fallas ja. EMBO Rep. 2021 Dec 6;22(12):e53471. doi: 10.15252/embr.202153471. Epub 2021 Oct 26. EMBO Rep. 2021. PMID: 34698433 Free PMC article.
Generation of ordered protein assemblies using rigid three-body fusion.
Vulovic I, Yao Q, Park YJ, Courbet A, Norris A, Busch F, Sahasrabuddhe A, Merten H, Sahtoe DD, Ueda G, Fallas JA, Weaver SJ, Hsia Y, Langan RA, Plückthun A, Wysocki VH, Veesler D, Jensen GJ, Baker D. Vulovic I, et al. Among authors: fallas ja. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2015037118. doi: 10.1073/pnas.2015037118. Proc Natl Acad Sci U S A. 2021. PMID: 34074752 Free PMC article.
32 results