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α4-α5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death.
Int J Mol Sci. 2023 Jan 1;24(1):748. doi: 10.3390/ijms24010748.
Int J Mol Sci. 2023.
PMID: 36614192
Free PMC article.
Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds.
Pallara C, Cabot D, Rivas J, Brun S, Seco J, Abuasaker B, Tarragó T, Jaumot M, Prades R, Agell N.
Pallara C, et al. Among authors: abuasaker b.
Sci Rep. 2022 Sep 22;12(1):15810. doi: 10.1038/s41598-022-19703-6.
Sci Rep. 2022.
PMID: 36138080
Free PMC article.
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KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer.
Cabot D, Brun S, Paco N, Ginesta MM, Gendrau-Sanclemente N, Abuasaker B, Ruiz-Fariña T, Barceló C, Cuatrecasas M, Bosch M, Rentero C, Pons G, Estanyol JM, Capellà G, Jaumot M, Agell N.
Cabot D, et al. Among authors: abuasaker b.
Oncogene. 2021 Sep;40(38):5730-5740. doi: 10.1038/s41388-021-01967-3. Epub 2021 Jul 31.
Oncogene. 2021.
PMID: 34333552
Free article.
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