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Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation.
Johnson JL, Meneses-Salas E, Ramadass M, Monfregola J, Rahman F, Carvalho Gontijo R, Kiosses WB, Pestonjamasp K, Allen D, Zhang J, Osborne DG, Zhu YP, Wineinger N, Askari K, Chen D, Yu J, Henderson SC, Hedrick CC, Ursini MV, Grinstein S, Billadeau DD, Catz SD. Johnson JL, et al. Among authors: ramadass m. Nat Commun. 2022 Sep 21;13(1):5529. doi: 10.1038/s41467-022-33230-y. Nat Commun. 2022. PMID: 36130971 Free PMC article.
Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.
Johnson JL, Ramadass M, He J, Brown SJ, Zhang J, Abgaryan L, Biris N, Gavathiotis E, Rosen H, Catz SD. Johnson JL, et al. Among authors: ramadass m. J Biol Chem. 2016 Dec 9;291(50):25965-25982. doi: 10.1074/jbc.M116.741884. Epub 2016 Oct 4. J Biol Chem. 2016. PMID: 27702998 Free PMC article.
The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy.
Johnson JL, Ramadass M, Rahman F, Meneses-Salas E, Zgajnar NR, Carvalho Gontijo R, Zhang J, Kiosses WB, Zhu YP, Hedrick CC, Perego M, Gunton JE, Pestonjamasp K, Napolitano G, Catz SD. Johnson JL, et al. Among authors: ramadass m. J Leukoc Biol. 2021 Oct;110(4):629-649. doi: 10.1002/JLB.2HI0421-123R. Epub 2021 Jun 4. J Leukoc Biol. 2021. PMID: 34085299
21 results