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ORP5/8 and MIB/MICOS link ER-mitochondria and intra-mitochondrial contacts for non-vesicular transport of phosphatidylserine.
Monteiro-Cardoso VF, Rochin L, Arora A, Houcine A, Jääskeläinen E, Kivelä AM, Sauvanet C, Le Bars R, Marien E, Dehairs J, Neveu J, El Khallouki N, Santonico E, Swinnen JV, Tareste D, Olkkonen VM, Giordano F. Monteiro-Cardoso VF, et al. Among authors: rochin l. Cell Rep. 2022 Sep 20;40(12):111364. doi: 10.1016/j.celrep.2022.111364. Cell Rep. 2022. PMID: 36130504 Free article.
Chemical targeting of NEET proteins reveals their function in mitochondrial morphodynamics.
Molino D, Pila-Castellanos I, Marjault HB, Dias Amoedo N, Kopp K, Rochin L, Karmi O, Sohn YS, Lines L, Hamaï A, Joly S, Radreau P, Vonderscher J, Codogno P, Giordano F, Machin P, Rossignol R, Meldrum E, Arnoult D, Ruggieri A, Nechushtai R, de Chassey B, Morel E. Molino D, et al. Among authors: rochin l. EMBO Rep. 2020 Dec 3;21(12):e49019. doi: 10.15252/embr.201949019. Epub 2020 Nov 12. EMBO Rep. 2020. PMID: 33180995 Free PMC article.
PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration.
Sassano ML, van Vliet AR, Vervoort E, Van Eygen S, Van den Haute C, Pavie B, Roels J, Swinnen JV, Spinazzi M, Moens L, Casteels K, Meyts I, Pinton P, Marchi S, Rochin L, Giordano F, Felipe-Abrio B, Agostinis P. Sassano ML, et al. Among authors: rochin l. J Cell Biol. 2023 Mar 6;222(3):e202206008. doi: 10.1083/jcb.202206008. Epub 2023 Feb 23. J Cell Biol. 2023. PMID: 36821088 Free PMC article.
Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.
Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W. Sannerud R, et al. Among authors: rochin l. Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9. Cell. 2016. PMID: 27293189 Free PMC article.
BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.
Rochin L, Hurbain I, Serneels L, Fort C, Watt B, Leblanc P, Marks MS, De Strooper B, Raposo G, van Niel G. Rochin L, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10658-63. doi: 10.1073/pnas.1220748110. Epub 2013 Jun 10. Proc Natl Acad Sci U S A. 2013. PMID: 23754390 Free PMC article.
Parkinson's Disease: A Traffic Jam?
Clague MJ, Rochin L. Clague MJ, et al. Among authors: rochin l. Curr Biol. 2016 Apr 25;26(8):R332-4. doi: 10.1016/j.cub.2016.03.001. Curr Biol. 2016. PMID: 27115692 Free article.