Haeggström JZ - Search Results

1

Structures of Leukotriene Biosynthetic Enzymes and Development of New Therapeutics.

Haeggström JZ, Newcomer ME. Haeggström JZ, et al. Annu Rev Pharmacol Toxicol. 2023 Jan 20;63:407-428. doi: 10.1146/annurev-pharmtox-051921-085014. Epub 2022 Sep 21. Annu Rev Pharmacol Toxicol. 2023. PMID: 36130059 Free article. Review.

2

Structures and mechanisms of enzymes in the leukotriene cascade.

Rinaldo-Matthis A, Haeggström JZ. Rinaldo-Matthis A, et al. Among authors: haeggstrom jz. Biochimie. 2010 Jun;92(6):676-81. doi: 10.1016/j.biochi.2010.01.010. Epub 2010 Jan 22. Biochimie. 2010. PMID: 20097252 Review.

3

Human mast cells express two leukotriene C(4) synthase isoenzymes and the CysLT(1) receptor.

Sjöström M, Jakobsson PJ, Juremalm M, Ahmed A, Nilsson G, Macchia L, Haeggström JZ. Sjöström M, et al. Among authors: haeggstrom jz. Biochim Biophys Acta. 2002 Jun 13;1583(1):53-62. doi: 10.1016/s1388-1981(02)00160-9. Biochim Biophys Acta. 2002. PMID: 12069849

4

Leukotriene A4 hydrolase.

Haeggström JZ, Kull F, Rudberg PC, Tholander F, Thunnissen MM. Haeggström JZ, et al. Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:495-510. doi: 10.1016/s0090-6980(02)00051-5. Prostaglandins Other Lipid Mediat. 2002. PMID: 12432939 Review.

5

Structure and catalytic mechanisms of leukotriene A4 hydrolase.

Haeggström JZ, Tholander F, Wetterholm A. Haeggström JZ, et al. Prostaglandins Other Lipid Mediat. 2007 May;83(3):198-202. doi: 10.1016/j.prostaglandins.2007.01.006. Epub 2007 Jan 17. Prostaglandins Other Lipid Mediat. 2007. PMID: 17481555 Review.

6

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase.

Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggström JZ, Nordlund P. Martinez Molina D, et al. Among authors: haeggstrom jz. Nature. 2007 Aug 2;448(7153):613-6. doi: 10.1038/nature06009. Epub 2007 Jul 15. Nature. 2007. PMID: 17632546

7

Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy.

Sveinbjörnsson B, Rasmuson A, Baryawno N, Wan M, Pettersen I, Ponthan F, Orrego A, Haeggström JZ, Johnsen JI, Kogner P. Sveinbjörnsson B, et al. Among authors: haeggstrom jz. FASEB J. 2008 Oct;22(10):3525-36. doi: 10.1096/fj.07-103457. Epub 2008 Jun 30. FASEB J. 2008. PMID: 18591367

8

Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm.

Di Gennaro A, Wågsäter D, Mäyränpää MI, Gabrielsen A, Swedenborg J, Hamsten A, Samuelsson B, Eriksson P, Haeggström JZ. Di Gennaro A, et al. Among authors: haeggstrom jz. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21093-7. doi: 10.1073/pnas.1015166107. Epub 2010 Nov 15. Proc Natl Acad Sci U S A. 2010. PMID: 21078989 Free PMC article.

9

Targeting leukotriene B4 in inflammation.

Di Gennaro A, Haeggström JZ. Di Gennaro A, et al. Among authors: haeggstrom jz. Expert Opin Ther Targets. 2014 Jan;18(1):79-93. doi: 10.1517/14728222.2013.843671. Epub 2013 Oct 4. Expert Opin Ther Targets. 2014. PMID: 24090264

10

Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism.

Niegowski D, Kleinschmidt T, Olsson U, Ahmad S, Rinaldo-Matthis A, Haeggström JZ. Niegowski D, et al. Among authors: haeggstrom jz. J Biol Chem. 2014 Feb 21;289(8):5199-207. doi: 10.1074/jbc.M113.534628. Epub 2013 Dec 23. J Biol Chem. 2014. PMID: 24366866 Free PMC article.

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