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Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Romero-Ramirez A, Casas-Sánchez A, Autheman D, Duffy CW, Brandt C, Clare S, Harcourt K, André MR, de Almeida Castilho Neto KJG, Teixeira MMG, Machado RZ, Coombes J, Flynn RJ, Wright GJ, Jackson AP. Romero-Ramirez A, et al. Among authors: wright gj. PLoS Negl Trop Dis. 2022 Sep 21;16(9):e0010791. doi: 10.1371/journal.pntd.0010791. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36129968 Free PMC article.
Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection.
Crosnier C, Brandt C, Rinaldi G, McCarthy C, Barker C, Clare S, Berriman M, Wright GJ. Crosnier C, et al. Among authors: wright gj. Wellcome Open Res. 2019 Oct 16;4:159. doi: 10.12688/wellcomeopenres.15487.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31728414 Free PMC article.
Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers.
Crosnier C, Hokke CH, Protasio AV, Brandt C, Rinaldi G, Langenberg MCC, Clare S, Janse JJ, Wilson S, Berriman M, Roestenberg M, Wright GJ. Crosnier C, et al. Among authors: wright gj. J Infect Dis. 2022 Apr 19;225(8):1435-1446. doi: 10.1093/infdis/jiaa329. J Infect Dis. 2022. PMID: 32524140 Free PMC article.
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Awuah-Mensah G, McDonald J, Steketee PC, Autheman D, Whipple S, D'Archivio S, Brandt C, Clare S, Harcourt K, Wright GJ, Morrison LJ, Gadelha C, Wickstead B. Awuah-Mensah G, et al. Among authors: wright gj. PLoS Pathog. 2021 Jan 22;17(1):e1009224. doi: 10.1371/journal.ppat.1009224. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33481935 Free PMC article.
An invariant Trypanosoma vivax vaccine antigen induces protective immunity.
Autheman D, Crosnier C, Clare S, Goulding DA, Brandt C, Harcourt K, Tolley C, Galaway F, Khushu M, Ong H, Romero-Ramirez A, Duffy CW, Jackson AP, Wright GJ. Autheman D, et al. Among authors: wright gj. Nature. 2021 Jul;595(7865):96-100. doi: 10.1038/s41586-021-03597-x. Epub 2021 May 26. Nature. 2021. PMID: 34040257
A panel of recombinant Leishmania donovani cell surface and secreted proteins identifies LdBPK_323600.1 as a serological marker of symptomatic infection.
Roberts AJ, Ong HB, Clare S, Brandt C, Harcourt K, Takele Y, Ghosh P, Toepp A, Waugh M, Matano D, Färnert A, Adams E, Moreno J, Mbuchi M, Petersen C, Mondal D, Kropf P, Wright GJ. Roberts AJ, et al. Among authors: wright gj. mBio. 2024 May 8;15(5):e0085924. doi: 10.1128/mbio.00859-24. Epub 2024 Apr 19. mBio. 2024. PMID: 38639536 Free PMC article.
178 results