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Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Romero-Ramirez A, Casas-Sánchez A, Autheman D, Duffy CW, Brandt C, Clare S, Harcourt K, André MR, de Almeida Castilho Neto KJG, Teixeira MMG, Machado RZ, Coombes J, Flynn RJ, Wright GJ, Jackson AP. Romero-Ramirez A, et al. Among authors: brandt c. PLoS Negl Trop Dis. 2022 Sep 21;16(9):e0010791. doi: 10.1371/journal.pntd.0010791. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36129968 Free PMC article.
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice.
Lawley TD, Clare S, Walker AW, Stares MD, Connor TR, Raisen C, Goulding D, Rad R, Schreiber F, Brandt C, Deakin LJ, Pickard DJ, Duncan SH, Flint HJ, Clark TG, Parkhill J, Dougan G. Lawley TD, et al. Among authors: brandt c. PLoS Pathog. 2012;8(10):e1002995. doi: 10.1371/journal.ppat.1002995. Epub 2012 Oct 25. PLoS Pathog. 2012. PMID: 23133377 Free PMC article.
Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection.
Gimeno Brias S, Marsden M, Forbester J, Clement M, Brandt C, Harcourt K, Kane L, Chapman L, Clare S, Humphreys IR. Gimeno Brias S, et al. Among authors: brandt c. PLoS One. 2018 May 16;13(5):e0197596. doi: 10.1371/journal.pone.0197596. eCollection 2018. PLoS One. 2018. PMID: 29768502 Free PMC article.
Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection.
Crosnier C, Brandt C, Rinaldi G, McCarthy C, Barker C, Clare S, Berriman M, Wright GJ. Crosnier C, et al. Among authors: brandt c. Wellcome Open Res. 2019 Oct 16;4:159. doi: 10.12688/wellcomeopenres.15487.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31728414 Free PMC article.
High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.
Abeler-Dörner L, Laing AG, Lorenc A, Ushakov DS, Clare S, Speak AO, Duque-Correa MA, White JK, Ramirez-Solis R, Saran N, Bull KR, Morón B, Iwasaki J, Barton PR, Caetano S, Hng KI, Cambridge E, Forman S, Crockford TL, Griffiths M, Kane L, Harcourt K, Brandt C, Notley G, Babalola KO, Warren J, Mason JC, Meeniga A, Karp NA, Melvin D, Cawthorne E, Weinrick B, Rahim A, Drissler S, Meskas J, Yue A, Lux M, Song-Zhao GX, Chan A, Ballesteros Reviriego C, Abeler J, Wilson H, Przemska-Kosicka A, Edmans M, Strevens N, Pasztorek M, Meehan TF, Powrie F, Brinkman R, Dougan G, Jacobs W Jr, Lloyd CM, Cornall RJ, Maloy KJ, Grencis RK, Griffiths GM, Adams DJ, Hayday AC. Abeler-Dörner L, et al. Among authors: brandt c. Nat Immunol. 2020 Jan;21(1):86-100. doi: 10.1038/s41590-019-0549-0. Epub 2019 Dec 16. Nat Immunol. 2020. PMID: 31844327 Free PMC article.
Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers.
Crosnier C, Hokke CH, Protasio AV, Brandt C, Rinaldi G, Langenberg MCC, Clare S, Janse JJ, Wilson S, Berriman M, Roestenberg M, Wright GJ. Crosnier C, et al. Among authors: brandt c. J Infect Dis. 2022 Apr 19;225(8):1435-1446. doi: 10.1093/infdis/jiaa329. J Infect Dis. 2022. PMID: 32524140 Free PMC article.
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Awuah-Mensah G, McDonald J, Steketee PC, Autheman D, Whipple S, D'Archivio S, Brandt C, Clare S, Harcourt K, Wright GJ, Morrison LJ, Gadelha C, Wickstead B. Awuah-Mensah G, et al. Among authors: brandt c. PLoS Pathog. 2021 Jan 22;17(1):e1009224. doi: 10.1371/journal.ppat.1009224. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33481935 Free PMC article.
An invariant Trypanosoma vivax vaccine antigen induces protective immunity.
Autheman D, Crosnier C, Clare S, Goulding DA, Brandt C, Harcourt K, Tolley C, Galaway F, Khushu M, Ong H, Romero-Ramirez A, Duffy CW, Jackson AP, Wright GJ. Autheman D, et al. Among authors: brandt c. Nature. 2021 Jul;595(7865):96-100. doi: 10.1038/s41586-021-03597-x. Epub 2021 May 26. Nature. 2021. PMID: 34040257
1,585 results