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Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation.
Brock VJ, Lory NC, Möckl F, Birus M, Stähler T, Woelk LM, Jaeckstein M, Heeren J, Koch-Nolte F, Rissiek B, Mittrücker HW, Guse AH, Werner R, Diercks BP. Brock VJ, et al. Among authors: heeren j. Front Immunol. 2024 Feb 15;15:1258119. doi: 10.3389/fimmu.2024.1258119. eCollection 2024. Front Immunol. 2024. PMID: 38426095 Free PMC article.
The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice.
Benzi A, Heine M, Spinelli S, Salis A, Worthmann A, Diercks B, Astigiano C, Pérez Mato R, Memushaj A, Sturla L, Vellone V, Damonte G, Jaeckstein MY, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Heeren J, Bruzzone S. Benzi A, et al. Among authors: heeren j. Front Endocrinol (Lausanne). 2024 Feb 6;14:1251351. doi: 10.3389/fendo.2023.1251351. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38390373 Free PMC article.
EPAC1 enhances brown fat growth and beige adipogenesis.
Reverte-Salisa L, Siddig S, Hildebrand S, Yao X, Zurkovic J, Jaeckstein MY, Heeren J, Lezoualc'h F, Krahmer N, Pfeifer A. Reverte-Salisa L, et al. Among authors: heeren j. Nat Cell Biol. 2024 Jan;26(1):113-123. doi: 10.1038/s41556-023-01311-9. Epub 2024 Jan 9. Nat Cell Biol. 2024. PMID: 38195707 Free PMC article.
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Worthmann A, Ridder J, Piel SYL, Evangelakos I, Musfeldt M, Voß H, O'Farrell M, Fischer AW, Adak S, Sundd M, Siffeti H, Haumann F, Kloth K, Bierhals T, Heine M, Pertzborn P, Pauly M, Scholz JJ, Kundu S, Fuh MM, Neu A, Tödter K, Hempel M, Knippschild U, Semenkovich CF, Schlüter H, Heeren J, Scheja L, Kubisch C, Schlein C. Worthmann A, et al. Among authors: heeren j. Nat Commun. 2024 Jan 2;15(1):45. doi: 10.1038/s41467-023-44364-y. Nat Commun. 2024. PMID: 38167725 Free PMC article.
Abandonment of Routine Radiotherapy for Nonlocally Advanced Rectal Cancer and Oncological Outcomes.
Hazen SJA, Sluckin TC, Intven MPW, Beets GL, Beets-Tan RGH, Borstlap WAA, Buffart TE, Buijsen J, Burger JWA, van Dieren S, Furnée EJB, Geijsen ED, Hompes R, Horsthuis K, Leijtens JWA, Maas M, Melenhorst J, Nederend J, Peeters KCMJ, Rozema T, Tuynman JB, Verhoef C, de Vries M, van Westreenen HL, de Wilt JHW, Zimmerman DDE, Marijnen CAM, Tanis PJ, Kusters M; Dutch Snapshot Research Group. Hazen SJA, et al. JAMA Oncol. 2024 Feb 1;10(2):202-211. doi: 10.1001/jamaoncol.2023.5444. JAMA Oncol. 2024. PMID: 38127337
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M. Moschandrea C, et al. Among authors: heeren j. Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20. Nature. 2024. PMID: 38123683 Free PMC article.
Short-term dietary changes can result in mucosal and systemic immune depression.
Siracusa F, Schaltenberg N, Kumar Y, Lesker TR, Steglich B, Liwinski T, Cortesi F, Frommann L, Diercks BP, Bönisch F, Fischer AW, Scognamiglio P, Pauly MJ, Casar C, Cohen Y, Pelczar P, Agalioti T, Delfs F, Worthmann A, Wahib R, Jagemann B, Mittrücker HW, Kretz O, Guse AH, Izbicki JR, Lassen KG, Strowig T, Schweizer M, Villablanca EJ, Elinav E, Huber S, Heeren J, Gagliani N. Siracusa F, et al. Among authors: heeren j. Nat Immunol. 2023 Sep;24(9):1473-1486. doi: 10.1038/s41590-023-01587-x. Epub 2023 Aug 14. Nat Immunol. 2023. PMID: 37580603 Free PMC article.
236 results