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Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder.
Medici G, Tassinari M, Galvani G, Bastianini S, Gennaccaro L, Loi M, Mottolese N, Alvente S, Berteotti C, Sagona G, Lupori L, Candini G, Baggett HR, Zoccoli G, Giustetto M, Muotri A, Pizzorusso T, Nakai H, Trazzi S, Ciani E. Medici G, et al. Among authors: giustetto m. Neurotherapeutics. 2022 Oct;19(6):1886-1904. doi: 10.1007/s13311-022-01295-8. Epub 2022 Sep 15. Neurotherapeutics. 2022. PMID: 36109452 Free PMC article.
Synaptic determinants of rett syndrome.
Boggio EM, Lonetti G, Pizzorusso T, Giustetto M. Boggio EM, et al. Among authors: giustetto m. Front Synaptic Neurosci. 2010 Aug 6;2:28. doi: 10.3389/fnsyn.2010.00028. eCollection 2010. Front Synaptic Neurosci. 2010. PMID: 21423514 Free PMC article.
Mapping pathological phenotypes in a mouse model of CDKL5 disorder.
Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Vyssotski AL, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross CT. Amendola E, et al. Among authors: giustetto m. PLoS One. 2014 May 16;9(5):e91613. doi: 10.1371/journal.pone.0091613. eCollection 2014. PLoS One. 2014. PMID: 24838000 Free PMC article.
Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.
Morello N, Schina R, Pilotto F, Phillips M, Melani R, Plicato O, Pizzorusso T, Pozzo-Miller L, Giustetto M. Morello N, et al. Among authors: giustetto m. eNeuro. 2018 Sep 24;5(5):ENEURO.0086-18.2018. doi: 10.1523/ENEURO.0086-18.2018. eCollection 2018 Sep-Oct. eNeuro. 2018. PMID: 30255129 Free PMC article.
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder.
Gennaccaro L, Fuchs C, Loi M, Roncacè V, Trazzi S, Ait-Bali Y, Galvani G, Berardi AC, Medici G, Tassinari M, Ren E, Rimondini R, Giustetto M, Aicardi G, Ciani E. Gennaccaro L, et al. Among authors: giustetto m. Neurobiol Dis. 2021 Jun;153:105304. doi: 10.1016/j.nbd.2021.105304. Epub 2021 Feb 20. Neurobiol Dis. 2021. PMID: 33621640 Free article.
Age-Related Cognitive and Motor Decline in a Mouse Model of CDKL5 Deficiency Disorder is Associated with Increased Neuronal Senescence and Death.
Gennaccaro L, Fuchs C, Loi M, Pizzo R, Alvente S, Berteotti C, Lupori L, Sagona G, Galvani G, Gurgone A, Raspanti A, Medici G, Tassinari M, Trazzi S, Ren E, Rimondini R, Pizzorusso T, Zoccoli G, Giustetto M, Ciani E. Gennaccaro L, et al. Among authors: giustetto m. Aging Dis. 2021 Jun 1;12(3):764-785. doi: 10.14336/AD.2020.0827. eCollection 2021 Jun. Aging Dis. 2021. PMID: 34094641 Free PMC article.
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder.
Gurgone A, Pizzo R, Raspanti A, Chiantia G, Devi S, Comai D, Morello N, Pilotto F, Gnavi S, Lupori L, Mazziotti R, Sagona G, Putignano E, Nocentini A, Supuran CT, Marcantoni A, Pizzorusso T, Giustetto M. Gurgone A, et al. Among authors: giustetto m. Neuropsychopharmacology. 2023 May;48(6):877-886. doi: 10.1038/s41386-022-01412-3. Epub 2022 Aug 9. Neuropsychopharmacology. 2023. PMID: 35945276 Free PMC article.
63 results