Egan SE - Search Results

1

Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.

Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D. Langille E, et al. Among authors: egan se. Cancer Discov. 2022 Dec 2;12(12):2930-2953. doi: 10.1158/2159-8290.CD-21-0865. Cancer Discov. 2022. PMID: 36108220 Free PMC article.

2

Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.

Adams JR, Xu K, Liu JC, Agamez NM, Loch AJ, Wong RG, Wang W, Wright KL, Lane TF, Zacksenhaus E, Egan SE. Adams JR, et al. Among authors: egan se. Cancer Res. 2011 Apr 1;71(7):2706-17. doi: 10.1158/0008-5472.CAN-10-0738. Epub 2011 Feb 15. Cancer Res. 2011. PMID: 21324922

3

RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.

Jiang Z, Jones R, Liu JC, Deng T, Robinson T, Chung PE, Wang S, Herschkowitz JI, Egan SE, Perou CM, Zacksenhaus E. Jiang Z, et al. Among authors: egan se. Cell Cycle. 2011 May 15;10(10):1563-70. doi: 10.4161/cc.10.10.15703. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21502814 Review.

4

Elevated PI3K signaling drives multiple breast cancer subtypes.

Adams JR, Schachter NF, Liu JC, Zacksenhaus E, Egan SE. Adams JR, et al. Among authors: egan se. Oncotarget. 2011 Jun;2(6):435-47. doi: 10.18632/oncotarget.285. Oncotarget. 2011. PMID: 21646685 Free PMC article. Review.

5

Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ERα- breast cancer.

Liu JC, Voisin V, Bader GD, Deng T, Pusztai L, Symmans WF, Esteva FJ, Egan SE, Zacksenhaus E. Liu JC, et al. Among authors: egan se. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5832-7. doi: 10.1073/pnas.1201105109. Epub 2012 Mar 28. Proc Natl Acad Sci U S A. 2012. PMID: 22460789 Free PMC article.

6

A Tumor initiating cell-enriched prognostic signature for HER2+:ERα- breast cancer; rationale, new features, controversies and future directions.

Liu JC, Egan SE, Zacksenhaus E. Liu JC, et al. Among authors: egan se. Oncotarget. 2013 Aug;4(8):1317-28. doi: 10.18632/oncotarget.1170. Oncotarget. 2013. PMID: 23945331 Free PMC article.

7

High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors.

Robinson TJ, Pai M, Liu JC, Vizeacoumar F, Sun T, Egan SE, Datti A, Huang J, Zacksenhaus E. Robinson TJ, et al. Among authors: egan se. Cell Cycle. 2013 Sep 15;12(18):3013-24. doi: 10.4161/cc.26063. Epub 2013 Aug 12. Cell Cycle. 2013. PMID: 23974104 Free PMC article.

8

RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs.

Robinson TJ, Liu JC, Vizeacoumar F, Sun T, Maclean N, Egan SE, Schimmer AD, Datti A, Zacksenhaus E. Robinson TJ, et al. Among authors: egan se. PLoS One. 2013 Nov 12;8(11):e78641. doi: 10.1371/journal.pone.0078641. eCollection 2013. PLoS One. 2013. PMID: 24265703 Free PMC article.

9

shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer.

Deng T, Liu JC, Chung PE, Uehling D, Aman A, Joseph B, Ketela T, Jiang Z, Schachter NF, Rottapel R, Egan SE, Al-Awar R, Moffat J, Zacksenhaus E. Deng T, et al. Among authors: egan se. Cancer Res. 2014 Apr 1;74(7):2119-30. doi: 10.1158/0008-5472.CAN-13-2138. Epub 2014 Jan 31. Cancer Res. 2014. PMID: 24487029

10

Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K.

Liu JC, Voisin V, Wang S, Wang DY, Jones RA, Datti A, Uehling D, Al-awar R, Egan SE, Bader GD, Tsao M, Mak TW, Zacksenhaus E. Liu JC, et al. Among authors: egan se. EMBO Mol Med. 2014 Dec;6(12):1542-60. doi: 10.15252/emmm.201404402. EMBO Mol Med. 2014. PMID: 25330770 Free PMC article.

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