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Double-strand break toxicity is chromatin context independent.
Friskes A, Koob L, Krenning L, Severson TM, Koeleman ES, Vergara X, Schubert M, van den Berg J, Evers B, Manjón AG, Joosten S, Kim Y, Zwart W, Medema RH. Friskes A, et al. Among authors: evers b. Nucleic Acids Res. 2022 Sep 23;50(17):9930-9947. doi: 10.1093/nar/gkac758. Nucleic Acids Res. 2022. PMID: 36107780 Free PMC article.
ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.
Berns K, Caumanns JJ, Hijmans EM, Gennissen AMC, Severson TM, Evers B, Wisman GBA, Jan Meersma G, Lieftink C, Beijersbergen RL, Itamochi H, van der Zee AGJ, de Jong S, Bernards R. Berns K, et al. Among authors: evers b. Oncogene. 2018 Aug;37(33):4611-4625. doi: 10.1038/s41388-018-0300-6. Epub 2018 May 15. Oncogene. 2018. PMID: 29760405 Free PMC article.
The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.
Barazas M, Annunziato S, Pettitt SJ, de Krijger I, Ghezraoui H, Roobol SJ, Lutz C, Frankum J, Song FF, Brough R, Evers B, Gogola E, Bhin J, van de Ven M, van Gent DC, Jacobs JJL, Chapman R, Lord CJ, Jonkers J, Rottenberg S. Barazas M, et al. Among authors: evers b. Cell Rep. 2018 May 15;23(7):2107-2118. doi: 10.1016/j.celrep.2018.04.046. Cell Rep. 2018. PMID: 29768208 Free PMC article.
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.
Desmet CJ, Gallenne T, Prieur A, Reyal F, Visser NL, Wittner BS, Smit MA, Geiger TR, Laoukili J, Iskit S, Rodenko B, Zwart W, Evers B, Horlings H, Ajouaou A, Zevenhoven J, van Vliet M, Ramaswamy S, Wessels LF, Peeper DS. Desmet CJ, et al. Among authors: evers b. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5139-44. doi: 10.1073/pnas.1222085110. Epub 2013 Mar 12. Proc Natl Acad Sci U S A. 2013. PMID: 23483055 Free PMC article.
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Among authors: evers b. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108662 Free PMC article.
541 results