Hurley JH - Search Results

1

Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.

Jansen RM, Peruzzo R, Fromm SA, Yokom AL, Zoncu R, Hurley JH. Jansen RM, et al. Among authors: hurley jh. Sci Adv. 2022 Sep 16;8(37):eadd2926. doi: 10.1126/sciadv.add2926. Epub 2022 Sep 14. Sci Adv. 2022. PMID: 36103527 Free PMC article.

2

Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy.

Young LN, Cho K, Lawrence R, Zoncu R, Hurley JH. Young LN, et al. Among authors: hurley jh. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8224-9. doi: 10.1073/pnas.1603650113. Epub 2016 Jul 6. Proc Natl Acad Sci U S A. 2016. PMID: 27385829 Free PMC article.

3

Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.

Su MY, Morris KL, Kim DJ, Fu Y, Lawrence R, Stjepanovic G, Zoncu R, Hurley JH. Su MY, et al. Among authors: hurley jh. Mol Cell. 2017 Dec 7;68(5):835-846.e3. doi: 10.1016/j.molcel.2017.10.016. Epub 2017 Nov 5. Mol Cell. 2017. PMID: 29107538 Free PMC article.

4

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.

Lawrence RE, Cho KF, Rappold R, Thrun A, Tofaute M, Kim DJ, Moldavski O, Hurley JH, Zoncu R. Lawrence RE, et al. Among authors: hurley jh. Nat Cell Biol. 2018 Sep;20(9):1052-1063. doi: 10.1038/s41556-018-0148-6. Epub 2018 Jul 30. Nat Cell Biol. 2018. PMID: 30061680 Free PMC article.

5

Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.

Horst BG, Yokom AL, Rosenberg DJ, Morris KL, Hammel M, Hurley JH, Marletta MA. Horst BG, et al. Among authors: hurley jh. Elife. 2019 Sep 30;8:e50634. doi: 10.7554/eLife.50634. Elife. 2019. PMID: 31566566 Free PMC article.

6

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.

Lawrence RE, Fromm SA, Fu Y, Yokom AL, Kim DJ, Thelen AM, Young LN, Lim CY, Samelson AJ, Hurley JH, Zoncu R. Lawrence RE, et al. Among authors: hurley jh. Science. 2019 Nov 22;366(6468):971-977. doi: 10.1126/science.aax0364. Epub 2019 Oct 31. Science. 2019. PMID: 31672913 Free PMC article.

7

A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.

Flower TG, Takahashi Y, Hudait A, Rose K, Tjahjono N, Pak AJ, Yokom AL, Liang X, Wang HG, Bouamr F, Voth GA, Hurley JH. Flower TG, et al. Among authors: hurley jh. Nat Struct Mol Biol. 2020 Jun;27(6):570-580. doi: 10.1038/s41594-020-0426-4. Epub 2020 May 18. Nat Struct Mol Biol. 2020. PMID: 32424346 Free PMC article.

8

ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer.

Shi X, Yokom AL, Wang C, Young LN, Youle RJ, Hurley JH. Shi X, et al. Among authors: hurley jh. J Cell Biol. 2020 Jul 6;219(7):e201911047. doi: 10.1083/jcb.201911047. J Cell Biol. 2020. PMID: 32516362 Free PMC article.

9

The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment.

Shi X, Chang C, Yokom AL, Jensen LE, Hurley JH. Shi X, et al. Among authors: hurley jh. Elife. 2020 Aug 10;9:e59099. doi: 10.7554/eLife.59099. Elife. 2020. PMID: 32773036 Free PMC article.

10

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD.

Su MY, Fromm SA, Zoncu R, Hurley JH. Su MY, et al. Among authors: hurley jh. Nature. 2020 Sep;585(7824):251-255. doi: 10.1038/s41586-020-2633-x. Epub 2020 Aug 26. Nature. 2020. PMID: 32848248 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

258 results

Search Page