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Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. Among authors: thomas r. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection.
Chamberland A, Sylla M, Boulassel MR, Baril JG, Côté P, Thomas R, Trottier B, Rouleau D, Routy JP, Tremblay C; Investigators of the Primary HIV-Infection Cohort of Montreal. Chamberland A, et al. Among authors: thomas r. Int J STD AIDS. 2011 Mar;22(3):146-50. doi: 10.1258/ijsa.2010.010292. Int J STD AIDS. 2011. PMID: 21464451
HLA class I, KIR, and genome-wide SNP diversity in the RV144 Thai phase 3 HIV vaccine clinical trial.
Prentice HA, Ehrenberg PK, Baldwin KM, Geretz A, Andrews C, Nitayaphan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, O'Connell RJ, Robb ML, Kim JH, Michael NL, Thomas R. Prentice HA, et al. Among authors: thomas r. Immunogenetics. 2014 May;66(5):299-310. doi: 10.1007/s00251-014-0765-6. Epub 2014 Mar 29. Immunogenetics. 2014. PMID: 24682434 Clinical Trial.
HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition.
Prentice HA, Tomaras GD, Geraghty DE, Apps R, Fong Y, Ehrenberg PK, Rolland M, Kijak GH, Krebs SJ, Nelson W, DeCamp A, Shen X, Yates NL, Zolla-Pazner S, Nitayaphan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Ferrari G, McElrath MJ, Montefiori DC, Bailer RT, Koup RA, O'Connell RJ, Robb ML, Michael NL, Gilbert PB, Kim JH, Thomas R. Prentice HA, et al. Among authors: thomas r. Sci Transl Med. 2015 Jul 15;7(296):296ra112. doi: 10.1126/scitranslmed.aab4005. Sci Transl Med. 2015. PMID: 26180102 Free PMC article.
HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders.
Janes H, Herbeck JT, Tovanabutra S, Thomas R, Frahm N, Duerr A, Hural J, Corey L, Self SG, Buchbinder SP, McElrath MJ, O'Connell RJ, Paris RM, Rerks-Ngarm S, Nitayaphan S, Pitisuttihum P, Kaewkungwal J, Robb ML, Michael NL, Mullins JI, Kim JH, Gilbert PB, Rolland M. Janes H, et al. Among authors: thomas r. Nat Med. 2015 Oct;21(10):1139-41. doi: 10.1038/nm.3932. Epub 2015 Aug 31. Nat Med. 2015. PMID: 26322580 Free PMC article.
Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
Kijak GH, Sanders-Buell E, Chenine AL, Eller MA, Goonetilleke N, Thomas R, Leviyang S, Harbolick EA, Bose M, Pham P, Oropeza C, Poltavee K, O'Sullivan AM, Billings E, Merbah M, Costanzo MC, Warren JA, Slike B, Li H, Peachman KK, Fischer W, Gao F, Cicala C, Arthos J, Eller LA, O'Connell RJ, Sinei S, Maganga L, Kibuuka H, Nitayaphan S, Rao M, Marovich MA, Krebs SJ, Rolland M, Korber BT, Shaw GM, Michael NL, Robb ML, Tovanabutra S, Kim JH. Kijak GH, et al. Among authors: thomas r. PLoS Pathog. 2017 Jul 31;13(7):e1006510. doi: 10.1371/journal.ppat.1006510. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28759651 Free PMC article.
8,246 results