Chomont N - Search Results

1

Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8⁺ T cells.

Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. Among authors: chomont n. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.

2

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, Boulassel MR, Delwart E, Sepulveda H, Balderas RS, Routy JP, Haddad EK, Sekaly RP. Trautmann L, et al. Among authors: chomont n. Nat Med. 2006 Oct;12(10):1198-202. doi: 10.1038/nm1482. Epub 2006 Aug 20. Nat Med. 2006. PMID: 16917489

3

[Inhibition of the PD-1 pathway restores the effector function of HIV-specific T cells].

Trautmann L, Chomont N, Sékaly RP. Trautmann L, et al. Among authors: chomont n. Med Sci (Paris). 2007 Jan;23(1):24-5. doi: 10.1051/medsci/200723124. Med Sci (Paris). 2007. PMID: 17212925 Free article. French. No abstract available.

4

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: chomont n. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149

5

Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection.

van Grevenynghe J, Halwani R, Chomont N, Ancuta P, Peretz Y, Tanel A, Procopio FA, shi Y, Said EA, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: chomont n. Semin Immunol. 2008 Jun;20(3):196-203. doi: 10.1016/j.smim.2008.07.008. Epub 2008 Aug 30. Semin Immunol. 2008. PMID: 18757210 Review.

6

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies.

Chomont N, Trautmann L, Routy JP, Sékaly RP. Chomont N, et al. Curr Opin HIV AIDS. 2007 Mar;2(2):116-22. doi: 10.1097/COH.0b013e3280287a4d. Curr Opin HIV AIDS. 2007. PMID: 19372876

7

Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections.

Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, El-Far M, Breton G, Haddad EK, Sekaly RP. Trautmann L, et al. Among authors: chomont n. Curr Opin HIV AIDS. 2007 May;2(3):219-27. doi: 10.1097/COH.0b013e3280ebb5c9. Curr Opin HIV AIDS. 2007. PMID: 19372890

8

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP. Chomont N, et al. Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21. Nat Med. 2009. PMID: 19543283 Free PMC article. Clinical Trial.

9

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

van Grevenynghe J, Cubas RA, Noto A, DaFonseca S, He Z, Peretz Y, Filali-Mouhim A, Dupuy FP, Procopio FA, Chomont N, Balderas RS, Said EA, Boulassel MR, Tremblay CL, Routy JP, Sékaly RP, Haddad EK. van Grevenynghe J, et al. Among authors: chomont n. J Clin Invest. 2011 Oct;121(10):3877-88. doi: 10.1172/JCI59211. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926463 Free PMC article.

10

The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid.

Wacleche VS, Chomont N, Gosselin A, Monteiro P, Goupil M, Kared H, Tremblay C, Bernard N, Boulassel MR, Routy JP, Ancuta P. Wacleche VS, et al. Among authors: chomont n. PLoS One. 2012;7(3):e32964. doi: 10.1371/journal.pone.0032964. Epub 2012 Mar 28. PLoS One. 2012. PMID: 22470433 Free PMC article.

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