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Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer.
Jeselsohn R, Yelensky R, Buchwalter G, Frampton G, Meric-Bernstam F, Gonzalez-Angulo AM, Ferrer-Lozano J, Perez-Fidalgo JA, Cristofanilli M, Gómez H, Arteaga CL, Giltnane J, Balko JM, Cronin MT, Jarosz M, Sun J, Hawryluk M, Lipson D, Otto G, Ross JS, Dvir A, Soussan-Gutman L, Wolf I, Rubinek T, Gilmore L, Schnitt S, Come SE, Pusztai L, Stephens P, Brown M, Miller VA. Jeselsohn R, et al. Clin Cancer Res. 2014 Apr 1;20(7):1757-1767. doi: 10.1158/1078-0432.CCR-13-2332. Epub 2014 Jan 7. Clin Cancer Res. 2014. PMID: 24398047 Free PMC article.
How drug resistance takes shape.
Jeselsohn R, Brown M. Jeselsohn R, et al. Elife. 2016 Mar 24;5:e14973. doi: 10.7554/eLife.14973. Elife. 2016. PMID: 27010172 Free PMC article.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Detre S, Dowsett M, Jeselsohn RM, Liu XS, Brown M. Xiao T, et al. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7869-7878. doi: 10.1073/pnas.1722617115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987050 Free PMC article.
Estrogen receptor signaling is reprogrammed during breast tumorigenesis.
Chi D, Singhal H, Li L, Xiao T, Liu W, Pun M, Jeselsohn R, He H, Lim E, Vadhi R, Rao P, Long H, Garber J, Brown M. Chi D, et al. Among authors: jeselsohn r. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11437-11443. doi: 10.1073/pnas.1819155116. Epub 2019 May 20. Proc Natl Acad Sci U S A. 2019. PMID: 31110002 Free PMC article.
GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers.
Bianco G, Coto-Llerena M, Gallon J, Kancherla V, Taha-Mehlitz S, Marinucci M, Konantz M, Srivatsa S, Montazeri H, Panebianco F, Tirunagaru VG, De Menna M, Paradiso V, Ercan C, Dahmani A, Montaudon E, Beerenwinkel N, Kruithof-de Julio M, Terracciano LM, Lengerke C, Jeselsohn RM, Doebele RC, Bidard FC, Marangoni E, Ng CKY, Piscuoglio S. Bianco G, et al. Commun Biol. 2022 Apr 19;5(1):373. doi: 10.1038/s42003-022-03296-x. Commun Biol. 2022. PMID: 35440675 Free PMC article.
70 results