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Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's.
Toomey CE, Heywood WE, Evans JR, Lachica J, Pressey SN, Foti SC, Al Shahrani M, D'Sa K, Hargreaves IP, Heales S, Orford M, Troakes C, Attems J, Gelpi E, Palkovits M, Lashley T, Gentleman SM, Revesz T, Mills K, Gandhi S. Toomey CE, et al. Among authors: palkovits m. Acta Neuropathol Commun. 2022 Sep 8;10(1):134. doi: 10.1186/s40478-022-01424-6. Acta Neuropathol Commun. 2022. PMID: 36076304 Free PMC article.
Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study.
Durrenberger PF, Fernando S, Kashefi SN, Ferrer I, Hauw JJ, Seilhean D, Smith C, Walker R, Al-Sarraj S, Troakes C, Palkovits M, Kasztner M, Huitinga I, Arzberger T, Dexter DT, Kretzschmar H, Reynolds R. Durrenberger PF, et al. Among authors: palkovits m. J Neuropathol Exp Neurol. 2010 Jan;69(1):70-81. doi: 10.1097/NEN.0b013e3181c7e32f. J Neuropathol Exp Neurol. 2010. PMID: 20010301
Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study.
Durrenberger PF, Fernando FS, Magliozzi R, Kashefi SN, Bonnert TP, Ferrer I, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Parchi P, Capellari S, Arzberger T, Kretzschmar H, Roncaroli F, Dexter DT, Reynolds R. Durrenberger PF, et al. Among authors: palkovits m. Acta Neuropathol. 2012 Dec;124(6):893-903. doi: 10.1007/s00401-012-1027-z. Epub 2012 Aug 5. Acta Neuropathol. 2012. PMID: 22864814
Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease.
Ádori C, Glück L, Barde S, Yoshitake T, Kovacs GG, Mulder J, Maglóczky Z, Havas L, Bölcskei K, Mitsios N, Uhlén M, Szolcsányi J, Kehr J, Rönnbäck A, Schwartz T, Rehfeld JF, Harkany T, Palkovits M, Schulz S, Hökfelt T. Ádori C, et al. Among authors: palkovits m. Acta Neuropathol. 2015 Apr;129(4):541-63. doi: 10.1007/s00401-015-1394-3. Epub 2015 Feb 13. Acta Neuropathol. 2015. PMID: 25676386 Free article.
The decrease of dopamine D₂/D₃ receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB₁ cannabinoid receptors in Parkinson's disease: a preliminary autoradiographic study with the selective dopamine D₂/D₃ antagonist [³H]raclopride and the novel CB₁ inverse agonist [¹²⁵I]SD7015.
Farkas S, Nagy K, Jia Z, Harkany T, Palkovits M, Donohou SR, Pike VW, Halldin C, Máthé D, Csiba L, Gulyás B. Farkas S, et al. Among authors: palkovits m. Brain Res Bull. 2012 Apr 10;87(6):504-10. doi: 10.1016/j.brainresbull.2012.02.012. Epub 2012 Mar 7. Brain Res Bull. 2012. PMID: 22421165 Free PMC article.
[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease.
Farkas S, Nagy K, Palkovits M, Kovács GG, Jia Z, Donohue S, Pike V, Halldin C, Máthé D, Harkany T, Gulyás B, Csiba L. Farkas S, et al. Among authors: palkovits m. Neurochem Int. 2012 Feb;60(3):286-91. doi: 10.1016/j.neuint.2011.11.004. Epub 2011 Dec 28. Neurochem Int. 2012. PMID: 22222721 Free PMC article.
717 results