Hargreaves IP - Search Results

1

Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's.

Toomey CE, Heywood WE, Evans JR, Lachica J, Pressey SN, Foti SC, Al Shahrani M, D'Sa K, Hargreaves IP, Heales S, Orford M, Troakes C, Attems J, Gelpi E, Palkovits M, Lashley T, Gentleman SM, Revesz T, Mills K, Gandhi S. Toomey CE, et al. Among authors: hargreaves ip. Acta Neuropathol Commun. 2022 Sep 8;10(1):134. doi: 10.1186/s40478-022-01424-6. Acta Neuropathol Commun. 2022. PMID: 36076304 Free PMC article.

2

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson's Disease.

Al Shahrani M, Heales S, Hargreaves I, Orford M. Al Shahrani M, et al. J Clin Med. 2017 Oct 27;6(11):100. doi: 10.3390/jcm6110100. J Clin Med. 2017. PMID: 29077060 Free PMC article. Review.

3

Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson's disease.

Foti SC, Hargreaves I, Carrington S, Kiely AP, Houlden H, Holton JL. Foti SC, et al. Sci Rep. 2019 Apr 25;9(1):6559. doi: 10.1038/s41598-019-42902-7. Sci Rep. 2019. PMID: 31024027 Free PMC article.

4

Drug-Induced Mitochondrial Toxicity.

Hargreaves IP, Al Shahrani M, Wainwright L, Heales SJ. Hargreaves IP, et al. Drug Saf. 2016 Jul;39(7):661-74. doi: 10.1007/s40264-016-0417-x. Drug Saf. 2016. PMID: 26992920 Review.

5

PINK1 protein in normal human brain and Parkinson's disease.

Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. Gandhi S, et al. Brain. 2006 Jul;129(Pt 7):1720-31. doi: 10.1093/brain/awl114. Epub 2006 May 15. Brain. 2006. PMID: 16702191

6

Mitochondrial disease: a historical, biochemical, and London perspective.

Land JM, Morgan-Hughes JA, Hargreaves I, Heales SJ. Land JM, et al. Neurochem Res. 2004 Mar;29(3):483-91. doi: 10.1023/b:nere.0000014819.53972.b0. Neurochem Res. 2004. PMID: 15038596 Review.

7

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease.

Dunn L, Allen GF, Mamais A, Ling H, Li A, Duberley KE, Hargreaves IP, Pope S, Holton JL, Lees A, Heales SJ, Bandopadhyay R. Dunn L, et al. Among authors: hargreaves ip. Neurobiol Aging. 2014 May;35(5):1111-5. doi: 10.1016/j.neurobiolaging.2013.11.001. Epub 2013 Nov 9. Neurobiol Aging. 2014. PMID: 24300239 Free PMC article.

8

Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis.

Ng X, Sadeghian M, Heales S, Hargreaves IP. Ng X, et al. Among authors: hargreaves ip. Int J Mol Sci. 2019 Oct 9;20(20):4975. doi: 10.3390/ijms20204975. Int J Mol Sci. 2019. PMID: 31600882 Free PMC article.

9

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, Duchen MR, Latchman D, Tabrizi SJ, Wood NW. Wood-Kaczmar A, et al. PLoS One. 2008 Jun 18;3(6):e2455. doi: 10.1371/journal.pone.0002455. PLoS One. 2008. PMID: 18560593 Free PMC article.

10

Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis.

Sadeghian M, Mastrolia V, Rezaei Haddad A, Mosley A, Mullali G, Schiza D, Sajic M, Hargreaves I, Heales S, Duchen MR, Smith KJ. Sadeghian M, et al. Sci Rep. 2016 Sep 14;6:33249. doi: 10.1038/srep33249. Sci Rep. 2016. PMID: 27624721 Free PMC article.

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