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Converting non-neutralizing SARS-CoV-2 antibodies into broad-spectrum inhibitors.
Nat Chem Biol. 2022 Nov;18(11):1270-1276. doi: 10.1038/s41589-022-01140-1. Epub 2022 Sep 8.
Nat Chem Biol. 2022.
PMID: 36076082
Free PMC article.
The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat.
Montefiori DC, Filsinger Interrante MV, Bell BN, Rubio AA, Joyce JG, Shiver JW, LaBranche CC, Kim PS.
Montefiori DC, et al. Among authors: bell bn.
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2018027118. doi: 10.1073/pnas.2018027118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33431684
Free PMC article.
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Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library.
Bell BN, Powell AE, Rodriguez C, Cochran JR, Kim PS.
Bell BN, et al.
Protein Sci. 2021 Apr;30(4):716-727. doi: 10.1002/pro.4044. Epub 2021 Feb 24.
Protein Sci. 2021.
PMID: 33586288
Free PMC article.
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A Derivative of the D5 Monoclonal Antibody That Targets the gp41 N-Heptad Repeat of HIV-1 with Broad Tier-2-Neutralizing Activity.
Rubio AA, Filsinger Interrante MV, Bell BN, Brown CL, Bruun TUJ, LaBranche CC, Montefiori DC, Kim PS.
Rubio AA, et al. Among authors: bell bn.
J Virol. 2021 Jul 12;95(15):e0235020. doi: 10.1128/JVI.02350-20. Epub 2021 Jul 12.
J Virol. 2021.
PMID: 33980592
Free PMC article.
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HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier.
Bell BN, Bruun TUJ, Friedland N, Kim PS.
Bell BN, et al.
Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215792120. doi: 10.1073/pnas.2215792120. Epub 2023 Feb 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 36795752
Free PMC article.
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Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL.
Grell TAJ, et al. Among authors: bell bn.
Protein Sci. 2019 Jan;28(1):202-215. doi: 10.1002/pro.3529.
Protein Sci. 2019.
PMID: 30341796
Free PMC article.
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