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Targeting BCL-XL in fibrolamellar hepatocellular carcinoma.
Shebl B, Ng D, Lalazar G, Rosemore C, Finkelstein TM, Migler RD, Zheng G, Zhang P, Jiang CS, Qureshi A, Vaughan R, Yarchoan M, de Jong YP, Rice CM, Coffino P, Ortiz MV, Zhou D, Simon SM. Shebl B, et al. Among authors: lalazar g. JCI Insight. 2022 Sep 8;7(17):e161820. doi: 10.1172/jci.insight.161820. JCI Insight. 2022. PMID: 36073545 Free PMC article.
Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.
Simon EP, Freije CA, Farber BA, Lalazar G, Darcy DG, Honeyman JN, Chiaroni-Clarke R, Dill BD, Molina H, Bhanot UK, La Quaglia MP, Rosenberg BR, Simon SM. Simon EP, et al. Among authors: lalazar g. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5916-25. doi: 10.1073/pnas.1424894112. Epub 2015 Oct 21. Proc Natl Acad Sci U S A. 2015. PMID: 26489647 Free PMC article.
DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.
Kastenhuber ER, Lalazar G, Houlihan SL, Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B, Wilkinson JE, Simon SM, Lowe SW. Kastenhuber ER, et al. Among authors: lalazar g. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13076-13084. doi: 10.1073/pnas.1716483114. Epub 2017 Nov 21. Proc Natl Acad Sci U S A. 2017. PMID: 29162699 Free PMC article.
Intracranial metastasis in fibrolamellar hepatocellular carcinoma.
Hammond WJ, Lalazar G, Saltsman JA, Farber BA, Danzer E, Sherpa TC, Banda CD, Andolina JR, Karimi S, Brennan CW, Torbenson MS, La Quaglia MP, Simon SM. Hammond WJ, et al. Among authors: lalazar g. Pediatr Blood Cancer. 2018 Apr;65(4):10.1002/pbc.26919. doi: 10.1002/pbc.26919. Epub 2017 Dec 29. Pediatr Blood Cancer. 2018. PMID: 29286561 Free PMC article.
Non coding RNA analysis in fibrolamellar hepatocellular carcinoma.
Farber BA, Lalazar G, Simon EP, Hammond WJ, Requena D, Bhanot UK, La Quaglia MP, Simon SM. Farber BA, et al. Among authors: lalazar g. Oncotarget. 2017 Dec 15;9(12):10211-10227. doi: 10.18632/oncotarget.23325. eCollection 2018 Feb 13. Oncotarget. 2017. PMID: 29535801 Free PMC article.
Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.
Lalazar G, Requena D, Ramos-Espiritu L, Ng D, Bhola PD, de Jong YP, Wang R, Narayan NJC, Shebl B, Levin S, Michailidis E, Kabbani M, Vercauteren KOA, Hurley AM, Farber BA, Hammond WJ, Saltsman JA 3rd, Weinberg EM, Glickman JF, Lyons BA, Ellison J, Schadde E, Hertl M, Leiting JL, Truty MJ, Smoot RL, Tierney F, Kato T, Wendel HG, LaQuaglia MP, Rice CM, Letai A, Coffino P, Torbenson MS, Ortiz MV, Simon SM. Lalazar G, et al. Cancer Discov. 2021 Oct;11(10):2544-2563. doi: 10.1158/2159-8290.CD-20-0872. Epub 2021 Jun 14. Cancer Discov. 2021. PMID: 34127480 Free PMC article.
Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States.
Zou C, El Dika I, Vercauteren KOA, Capanu M, Chou J, Shia J, Pilet J, Quirk C, Lalazar G, Andrus L, Kabbani M, Yaqubie A, Khalil D, Mergoub T, Chiriboga L, Rice CM, Abou-Alfa GK, de Jong YP. Zou C, et al. Among authors: lalazar g. Cancer Med. 2022 Feb;11(3):602-617. doi: 10.1002/cam4.4375. Epub 2021 Dec 24. Cancer Med. 2022. PMID: 34951132 Free PMC article.
Human liver organoids for disease modeling of fibrolamellar carcinoma.
Narayan NJC, Requena D, Lalazar G, Ramos-Espiritu L, Ng D, Levin S, Shebl B, Wang R, Hammond WJ, Saltsman JA 3rd, Gehart H, Torbenson MS, Clevers H, LaQuaglia MP, Simon SM. Narayan NJC, et al. Among authors: lalazar g. Stem Cell Reports. 2022 Aug 9;17(8):1874-1888. doi: 10.1016/j.stemcr.2022.06.003. Epub 2022 Jul 7. Stem Cell Reports. 2022. PMID: 35803261 Free PMC article.
57 results