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Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity.
Hangiu O, Compte M, Dinesen A, Navarro R, Tapia-Galisteo A, Mandrup OA, Erce-Llamazares A, Lázaro-Gorines R, Nehme-Álvarez D, Domínguez-Alonso C, Harwood SL, Alfonso C, Blanco B, Rubio-Pérez L, Jiménez-Reinoso A, Díez-Alonso L, Blanco FJ, Sanz L, Howard KA, Álvarez-Vallina L. Hangiu O, et al. Among authors: dinesen a. iScience. 2022 Aug 17;25(9):104958. doi: 10.1016/j.isci.2022.104958. eCollection 2022 Sep 16. iScience. 2022. PMID: 36072551 Free PMC article.
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation.
Dinesen A, Andersen VL, Elkhashab M, Pilati D, Bech P, Fuchs E, Samuelsen TR, Winther A, Cai Y, Märcher A, Wall A, Omer M, Nielsen JS, Chudasama V, Baker JR, Gothelf KV, Wengel J, Kjems J, Howard KA. Dinesen A, et al. Bioconjug Chem. 2024 Feb 21;35(2):214-222. doi: 10.1021/acs.bioconjchem.3c00491. Epub 2024 Jan 17. Bioconjug Chem. 2024. PMID: 38231391
In Vivo Study of the Inflammatory Tissue Response Surrounding a Novel Extended-Wear Kink-Resistant Insulin Infusion Set Prototype Compared With a Commercial Control Over Two Weeks of Wear Time.
Kastner JR, Eisler G, Torjman MC, Khalf A, Diaz D, Dinesen AR, Loeum C, Strasma PJ, Joseph JI. Kastner JR, et al. Among authors: dinesen ar. J Diabetes Sci Technol. 2023 Nov;17(6):1563-1572. doi: 10.1177/19322968221093362. Epub 2022 May 9. J Diabetes Sci Technol. 2023. PMID: 35533132 Free PMC article.
In vivo investigation of the tissue response to commercial Teflon insulin infusion sets in large swine for 14 days: the effect of angle of insertion on tissue histology and insulin spread within the subcutaneous tissue.
Eisler G, Kastner JR, Torjman MC, Khalf A, Diaz D, Dinesen AR, Loeum C, Thakur ML, Strasma P, Joseph JI. Eisler G, et al. Among authors: dinesen ar. BMJ Open Diabetes Res Care. 2019 Dec 8;7(1):e000881. doi: 10.1136/bmjdrc-2019-000881. eCollection 2019. BMJ Open Diabetes Res Care. 2019. PMID: 31875136 Free PMC article.
Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine.
Hauzenberger JR, Hipszer BR, Loeum C, McCue PA, DeStefano M, Torjman MC, Kaner MT, Dinesen AR, Chervoneva I, Pieber TR, Joseph JI. Hauzenberger JR, et al. Among authors: dinesen ar. Diabetes Technol Ther. 2017 Nov;19(11):641-650. doi: 10.1089/dia.2017.0175. Epub 2017 Oct 5. Diabetes Technol Ther. 2017. PMID: 28981324 Free PMC article.
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