Paton RS - Search Results

1

Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.

Belle R, Kamps JJAG, Poater J, Kumar K, Pieters BJGE, Salah E, Claridge TDW, Paton RS, Matthias Bickelhaupt F, Kawamura A, Schofield CJ, Mecinović J. Belle R, et al. Among authors: paton rs. Commun Chem. 2022 Mar 7;5(1):27. doi: 10.1038/s42004-022-00640-4. eCollection 2022 Dec. Commun Chem. 2022. PMID: 36071790 Free PMC article.

2

α- and α'-Lithiation-Electrophile Trapping of N-Thiopivaloyl and N-tert-Butoxythiocarbonyl α-Substituted Azetidines: Rationalization of the Regiodivergence Using NMR and Computation.

Jackson KE, Mortimer CL, Odell B, McKenna JM, Claridge TD, Paton RS, Hodgson DM. Jackson KE, et al. Among authors: paton rs. J Org Chem. 2015 Oct 16;80(20):9838-46. doi: 10.1021/acs.joc.5b01804. Epub 2015 Sep 24. J Org Chem. 2015. PMID: 26401908 Free article.

3

Investigations on recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition.

Choi H, Paton RS, Park H, Schofield CJ. Choi H, et al. Among authors: paton rs. Org Biomol Chem. 2016 Apr 26;14(17):4116-28. doi: 10.1039/c6ob00353b. Org Biomol Chem. 2016. PMID: 27072755 Free PMC article.

4

Mechanisms of histone lysine-modifying enzymes: A computational perspective on the role of the protein environment.

Cortopassi WA, Kumar K, Duarte F, Pimentel AS, Paton RS. Cortopassi WA, et al. Among authors: paton rs. J Mol Graph Model. 2016 Jun;67:69-84. doi: 10.1016/j.jmgm.2016.04.011. Epub 2016 May 4. J Mol Graph Model. 2016. PMID: 27258188

5

Cation-π interactions in CREBBP bromodomain inhibition: an electrostatic model for small-molecule binding affinity and selectivity.

Cortopassi WA, Kumar K, Paton RS. Cortopassi WA, et al. Among authors: paton rs. Org Biomol Chem. 2016 Nov 22;14(46):10926-10938. doi: 10.1039/c6ob02234k. Org Biomol Chem. 2016. PMID: 27814427

6

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

Zhang Z, Smart TJ, Choi H, Hardy F, Lohans CT, Abboud MI, Richardson MSW, Paton RS, McDonough MA, Schofield CJ. Zhang Z, et al. Among authors: paton rs. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4667-4672. doi: 10.1073/pnas.1617760114. Epub 2017 Apr 18. Proc Natl Acad Sci U S A. 2017. PMID: 28420789 Free PMC article.

7

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System.

Pliotas C, Grayer SC, Ekkerman S, Chan AKN, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JLP, Paton RS, Claridge TDW, Miller S, Booth IR, Naismith JH, Conway SJ. Pliotas C, et al. Among authors: paton rs. Biochemistry. 2017 Aug 15;56(32):4219-4234. doi: 10.1021/acs.biochem.7b00300. Epub 2017 Aug 4. Biochemistry. 2017. PMID: 28656748 Free PMC article.

8

C-H Cyanation of 6-Ring N-Containing Heteroaromatics.

Elbert BL, Farley AJM, Gorman TW, Johnson TC, Genicot C, Lallemand B, Pasau P, Flasz J, Castro JL, MacCoss M, Paton RS, Schofield CJ, Smith MD, Willis MC, Dixon DJ. Elbert BL, et al. Among authors: paton rs. Chemistry. 2017 Oct 20;23(59):14733-14737. doi: 10.1002/chem.201703931. Epub 2017 Sep 22. Chemistry. 2017. PMID: 28833674 Free PMC article.

9

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

Belle R, Al Temimi AHK, Kumar K, Pieters BJGE, Tumber A, Dunford JE, Johansson C, Oppermann U, Brown T, Schofield CJ, Hopkinson RJ, Paton RS, Kawamura A, Mecinović J. Belle R, et al. Among authors: paton rs. Chem Commun (Camb). 2017 Dec 12;53(99):13264-13267. doi: 10.1039/c7cc08028j. Chem Commun (Camb). 2017. PMID: 29186216 Free PMC article.

10

A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems through Lactone Formation.

Lohans CT, van Groesen E, Kumar K, Tooke CL, Spencer J, Paton RS, Brem J, Schofield CJ. Lohans CT, et al. Among authors: paton rs. Angew Chem Int Ed Engl. 2018 Jan 26;57(5):1282-1285. doi: 10.1002/anie.201711308. Epub 2018 Jan 5. Angew Chem Int Ed Engl. 2018. PMID: 29236332 Free PMC article.

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