Lei X - Search Results

1

Bile acids regulate the epithelial Na⁺ channel in native tissues through direct binding at multiple sites.

Wang XP, Tomilin V, Nickerson AJ, Tian R, Ertem M, McKernan A, Lei X, Pochynyuk O, Kashlan OB. Wang XP, et al. Among authors: lei x. J Physiol. 2022 Nov;600(21):4695-4711. doi: 10.1113/JP283318. Epub 2022 Sep 23. J Physiol. 2022. PMID: 36071685 Free PMC article.

2

Chemoproteomic Profiling Reveals the Mechanism of Bile Acid Tolerance in Bacteria.

Liu B, Zhuang S, Tian R, Liu Y, Wang Y, Lei X, Wang C. Liu B, et al. Among authors: lei x. ACS Chem Biol. 2022 Sep 16;17(9):2461-2470. doi: 10.1021/acschembio.2c00286. Epub 2022 Sep 1. ACS Chem Biol. 2022. PMID: 36049085

3

FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis.

Gao L, Su C, Du X, Wang R, Chen S, Zhou Y, Liu C, Liu X, Tian R, Zhang L, Xie K, Chen S, Guo Q, Guo L, Hano Y, Shimazaki M, Minami A, Oikawa H, Huang N, Houk KN, Huang L, Dai J, Lei X. Gao L, et al. Among authors: lei x. Nat Chem. 2020 Jul;12(7):620-628. doi: 10.1038/s41557-020-0467-7. Epub 2020 May 25. Nat Chem. 2020. PMID: 32451436

4

Chemoproteomic Profiling of Bile Acid Interacting Proteins.

Zhuang S, Li Q, Cai L, Wang C, Lei X. Zhuang S, et al. Among authors: lei x. ACS Cent Sci. 2017 May 24;3(5):501-509. doi: 10.1021/acscentsci.7b00134. Epub 2017 May 5. ACS Cent Sci. 2017. PMID: 28573213 Free PMC article.

5

MRGPRX4 is a bile acid receptor for human cholestatic itch.

Yu H, Zhao T, Liu S, Wu Q, Johnson O, Wu Z, Zhuang Z, Shi Y, Peng L, He R, Yang Y, Sun J, Wang X, Xu H, Zeng Z, Zou P, Lei X, Luo W, Li Y. Yu H, et al. Among authors: lei x. Elife. 2019 Sep 10;8:e48431. doi: 10.7554/eLife.48431. Elife. 2019. PMID: 31500698 Free PMC article.

6

A Novel Gene Alignment in Dorea sp. AM58-8 Produces 7-Dehydroxy-3β Bile Acids from Primary Bile Acids.

Bai Y, Zhao T, Gao M, Zou Y, Lei X. Bai Y, et al. Among authors: lei x. Biochemistry. 2022 Dec 20;61(24):2870-2878. doi: 10.1021/acs.biochem.2c00264. Epub 2022 Sep 21. Biochemistry. 2022. PMID: 36130198

7

Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.

Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J. Zhong Q, et al. Among authors: lei x. Cell Discov. 2022 Dec 22;8(1):137. doi: 10.1038/s41421-022-00502-2. Cell Discov. 2022. PMID: 36550107 Free PMC article.

8

C-H Glycosylation of Native Carboxylic Acids: Discovery of Antidiabetic SGLT-2 Inhibitors.

Wang S, Chen K, Guo F, Zhu W, Liu C, Dong H, Yu JQ, Lei X. Wang S, et al. Among authors: lei x. ACS Cent Sci. 2023 Jun 9;9(6):1129-1139. doi: 10.1021/acscentsci.3c00201. eCollection 2023 Jun 28. ACS Cent Sci. 2023. PMID: 37396867 Free PMC article.

9

Structural mechanism of SGLT1 inhibitors.

Niu Y, Cui W, Liu R, Wang S, Ke H, Lei X, Chen L. Niu Y, et al. Among authors: lei x. Nat Commun. 2022 Oct 28;13(1):6440. doi: 10.1038/s41467-022-33421-7. Nat Commun. 2022. PMID: 36307403 Free PMC article.

10

Structural basis of TRPV3 inhibition by an antagonist.

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X. Fan J, et al. Among authors: lei x. Nat Chem Biol. 2023 Jan;19(1):81-90. doi: 10.1038/s41589-022-01166-5. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302896

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