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Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma.
Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A. Nilsson M, et al. Drug Des Devel Ther. 2022 Aug 31;16:2901-2917. doi: 10.2147/DDDT.S354291. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36068788 Free PMC article.
Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata.
Mattsson J, Israelsson E, Björhall K, Yrlid LF, Thörn K, Thorén A, Toledo EA, Jinton L, Öberg L, Wingren C, Tapani S, Jackson SG, Skogberg G, Lundqvist AJ, Hendrickx R, Cavallin A, Österlund T, Grimster NP, Nilsson M, Åstrand A. Mattsson J, et al. Among authors: nilsson m. Skin Health Dis. 2023 Jan 29;3(3):e209. doi: 10.1002/ski2.209. eCollection 2023 Jun. Skin Health Dis. 2023. PMID: 37275428 Free PMC article.
Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization.
Nilsson M, Berggren K, Berglund S, Cerboni S, Collins M, Dahl G, Elmqvist D, Grimster NP, Hendrickx R, Johansson JR, Kettle JG, Lepistö M, Rhedin M, Smailagic A, Su Q, Wennberg T, Wu A, Österlund T, Naessens T, Mitra S. Nilsson M, et al. J Med Chem. 2023 Oct 12;66(19):13400-13415. doi: 10.1021/acs.jmedchem.3c00554. Epub 2023 Sep 22. J Med Chem. 2023. PMID: 37738648
Fragment-Based Discovery of Novel Allosteric MEK1 Binders.
Di Fruscia P, Edfeldt F, Shamovsky I, Collie GW, Aagaard A, Barlind L, Börjesson U, Hansson EL, Lewis RJ, Nilsson MK, Öster L, Pemberton J, Ripa L, Storer RI, Käck H. Di Fruscia P, et al. ACS Med Chem Lett. 2021 Jan 27;12(2):302-308. doi: 10.1021/acsmedchemlett.0c00563. eCollection 2021 Feb 11. ACS Med Chem Lett. 2021. PMID: 33603979 Free PMC article.
The 2024 Europe report of the Lancet Countdown on health and climate change: unprecedented warming demands unprecedented action.
van Daalen KR, Tonne C, Semenza JC, Rocklöv J, Markandya A, Dasandi N, Jankin S, Achebak H, Ballester J, Bechara H, Beck TM, Callaghan MW, Carvalho BM, Chambers J, Pradas MC, Courtenay O, Dasgupta S, Eckelman MJ, Farooq Z, Fransson P, Gallo E, Gasparyan O, Gonzalez-Reviriego N, Hamilton I, Hänninen R, Hatfield C, He K, Kazmierczak A, Kendrovski V, Kennard H, Kiesewetter G, Kouznetsov R, Kriit HK, Llabrés-Brustenga A, Lloyd SJ, Batista ML, Maia C, Martinez-Urtaza J, Mi Z, Milà C, Minx JC, Nieuwenhuijsen M, Palamarchuk J, Pantera DK, Quijal-Zamorano M, Rafaj P, Robinson EJZ, Sánchez-Valdivia N, Scamman D, Schmoll O, Sewe MO, Sherman JD, Singh P, Sirotkina E, Sjödin H, Sofiev M, Solaraju-Murali B, Springmann M, Treskova M, Triñanes J, Vanuytrecht E, Wagner F, Walawender M, Warnecke L, Zhang R, Romanello M, Antò JM, Nilsson M, Lowe R. van Daalen KR, et al. Among authors: nilsson m. Lancet Public Health. 2024 May 10:S2468-2667(24)00055-0. doi: 10.1016/S2468-2667(24)00055-0. Online ahead of print. Lancet Public Health. 2024. PMID: 38749451 Free article. Review. No abstract available.
2,427 results