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MicroRNA-125b-5p mimic inhibits acute liver failure.
Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann JH, Manns MP, Ott M, Cantz T, Sharma AD. Yang D, et al. Among authors: ott m. Nat Commun. 2016 Jun 23;7:11916. doi: 10.1038/ncomms11916. Nat Commun. 2016. PMID: 27336362 Free PMC article.
Expansion of functional personalized cells with specific transgene combinations.
Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, Truschel T, Luckner M, Köster M, MacLeod R, Pezoldt J, Hühn J, Yuan Q, Müller PP, Kempf H, Zweigerdt R, Dittrich-Breiholz O, Pufe T, Beckmann R, Drescher W, Riancho J, Sañudo C, Korff T, Opalka B, Rebmann V, Göthert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T. Lipps C, et al. Among authors: ott m. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4. Nat Commun. 2018. PMID: 29520052 Free PMC article.
Conversion of Fibroblasts to Hepatocyte-Like Cells In Vivo.
Song G, Yuan Q, Dai Z, Tsay HC, Shen X, Ott M, Sharma AD. Song G, et al. Among authors: ott m. Methods Mol Biol. 2019;1905:103-115. doi: 10.1007/978-1-4939-8961-4_10. Methods Mol Biol. 2019. PMID: 30536094
Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis.
Tsay HC, Yuan Q, Balakrishnan A, Kaiser M, Möbus S, Kozdrowska E, Farid M, Tegtmeyer PK, Borst K, Vondran FWR, Kalinke U, Kispert A, Manns MP, Ott M, Sharma AD. Tsay HC, et al. Among authors: ott m. J Hepatol. 2019 Apr;70(4):722-734. doi: 10.1016/j.jhep.2018.12.016. Epub 2018 Dec 22. J Hepatol. 2019. PMID: 30582979
Ex Vivo/In vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template.
Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, Sharma AD, Büning H, Ott M. Krooss SA, et al. Among authors: ott m. iScience. 2020 Jan 24;23(1):100764. doi: 10.1016/j.isci.2019.100764. Epub 2019 Dec 12. iScience. 2020. PMID: 31887661 Free PMC article.
Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B.
Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Krooss S, et al. Among authors: ott m. PLoS Genet. 2020 Apr 8;16(4):e1008690. doi: 10.1371/journal.pgen.1008690. eCollection 2020 Apr. PLoS Genet. 2020. PMID: 32267853 Free PMC article.
MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma.
Komoll RM, Hu Q, Olarewaju O, von Döhlen L, Yuan Q, Xie Y, Tsay HC, Daon J, Qin R, Manns MP, Sharma AD, Goga A, Ott M, Balakrishnan A. Komoll RM, et al. Among authors: ott m. J Hepatol. 2021 Jan;74(1):122-134. doi: 10.1016/j.jhep.2020.07.039. Epub 2020 Jul 30. J Hepatol. 2021. PMID: 32738449
1,245 results