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AAVvector-mediated in vivo reprogramming into pluripotency.
Senís E, Mosteiro L, Wilkening S, Wiedtke E, Nowrouzi A, Afzal S, Fronza R, Landerer H, Abad M, Niopek D, Schmidt M, Serrano M, Grimm D. Senís E, et al. Among authors: grimm d. Nat Commun. 2018 Jul 9;9(1):2651. doi: 10.1038/s41467-018-05059-x. Nat Commun. 2018. PMID: 29985406 Free PMC article.
Ex Vivo/In vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template.
Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, Sharma AD, Büning H, Ott M. Krooss SA, et al. Among authors: grimm d. iScience. 2020 Jan 24;23(1):100764. doi: 10.1016/j.isci.2019.100764. Epub 2019 Dec 12. iScience. 2020. PMID: 31887661 Free PMC article.
Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants.
Weinmann J, Weis S, Sippel J, Tulalamba W, Remes A, El Andari J, Herrmann AK, Pham QH, Borowski C, Hille S, Schönberger T, Frey N, Lenter M, VandenDriessche T, Müller OJ, Chuah MK, Lamla T, Grimm D. Weinmann J, et al. Among authors: grimm d. Nat Commun. 2020 Oct 28;11(1):5432. doi: 10.1038/s41467-020-19230-w. Nat Commun. 2020. PMID: 33116134 Free PMC article.
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models.
Hakim CH, Kumar SRP, Pérez-López DO, Wasala NB, Zhang D, Yue Y, Teixeira J, Pan X, Zhang K, Million ED, Nelson CE, Metzger S, Han J, Louderman JA, Schmidt F, Feng F, Grimm D, Smith BF, Yao G, Yang NN, Gersbach CA, Chen SJ, Herzog RW, Duan D. Hakim CH, et al. Among authors: grimm d. Nat Commun. 2021 Nov 24;12(1):6769. doi: 10.1038/s41467-021-26830-7. Nat Commun. 2021. PMID: 34819506 Free PMC article.
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch M, Schraft L, Chan A, Küchenhoff L, Rapti K, Ferreira AM, Kornienko J, Li S, Radke MH, Krämer C, Clauder-Münster S, Perlas E, Backs J, Gotthardt M, Dieterich C, van den Hoogenhof MMG, Grimm D, Steinmetz LM. Grosch M, et al. Among authors: grimm d. Nat Commun. 2023 Jun 22;14(1):3714. doi: 10.1038/s41467-023-39352-1. Nat Commun. 2023. PMID: 37349314 Free PMC article.
745 results