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HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury.
Autophagy. 2023 Apr;19(4):1199-1220. doi: 10.1080/15548627.2022.2119351. Epub 2022 Sep 9.
Autophagy. 2023.
PMID: 36048753
Free PMC article.
Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease.
White JA 2nd, Krzystek TJ, Hoffmar-Glennon H, Thant C, Zimmerman K, Iacobucci G, Vail J, Thurston L, Rahman S, Gunawardena S.
White JA 2nd, et al. Among authors: hoffmar glennon h.
Acta Neuropathol Commun. 2020 Jul 1;8(1):97. doi: 10.1186/s40478-020-00964-z.
Acta Neuropathol Commun. 2020.
PMID: 32611447
Free PMC article.
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