Jin J - Search Results

1

Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.

Cai WL, Chen JF, Chen H, Wingrove E, Kurley SJ, Chan LH, Zhang M, Arnal-Estape A, Zhao M, Balabaki A, Li W, Yu X, Krop ED, Dou Y, Liu Y, Jin J, Westbrook TF, Nguyen DX, Yan Q. Cai WL, et al. Among authors: jin j. Elife. 2022 Aug 31;11:e78163. doi: 10.7554/eLife.78163. Elife. 2022. PMID: 36043466 Free PMC article.

2

Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68).

Yu X, Huang XP, Kenakin TP, Slocum ST, Chen X, Martini ML, Liu J, Jin J. Yu X, et al. Among authors: jin j. J Med Chem. 2019 Aug 22;62(16):7557-7574. doi: 10.1021/acs.jmedchem.9b00869. Epub 2019 Aug 1. J Med Chem. 2019. PMID: 31298539 Free PMC article.

3

Designing Functionally Selective Noncatechol Dopamine D₁ Receptor Agonists with Potent In Vivo Antiparkinsonian Activity.

Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Martini ML, et al. Among authors: jin j. ACS Chem Neurosci. 2019 Sep 18;10(9):4160-4182. doi: 10.1021/acschemneuro.9b00410. Epub 2019 Aug 20. ACS Chem Neurosci. 2019. PMID: 31387346 Free PMC article.

4

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery.

Chiarella AM, Butler KV, Gryder BE, Lu D, Wang TA, Yu X, Pomella S, Khan J, Jin J, Hathaway NA. Chiarella AM, et al. Among authors: jin j. Nat Biotechnol. 2020 Jan;38(1):50-55. doi: 10.1038/s41587-019-0296-7. Epub 2019 Nov 11. Nat Biotechnol. 2020. PMID: 31712774 Free PMC article.

5

Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule Degraders.

Cheng M, Yu X, Lu K, Xie L, Wang L, Meng F, Han X, Chen X, Liu J, Xiong Y, Jin J. Cheng M, et al. Among authors: jin j. J Med Chem. 2020 Feb 13;63(3):1216-1232. doi: 10.1021/acs.jmedchem.9b01566. Epub 2020 Jan 14. J Med Chem. 2020. PMID: 31895569 Free PMC article.

6

Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders.

Shen Y, Gao G, Yu X, Kim H, Wang L, Xie L, Schwarz M, Chen X, Guccione E, Liu J, Bedford MT, Jin J. Shen Y, et al. Among authors: jin j. J Med Chem. 2020 Sep 10;63(17):9977-9989. doi: 10.1021/acs.jmedchem.0c01111. Epub 2020 Aug 21. J Med Chem. 2020. PMID: 32787082 Free PMC article.

7

Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogramming.

Tang Y, Zhao L, Yu X, Zhang J, Qian L, Jin J, Lu R, Zhou Y. Tang Y, et al. Among authors: jin j. Stem Cell Res. 2021 May;53:102365. doi: 10.1016/j.scr.2021.102365. Epub 2021 Apr 27. Stem Cell Res. 2021. PMID: 34087994 Free PMC article.

8

UV-induced reduction in Polycomb repression promotes epidermal pigmentation.

Li MY, Flora P, Pu H, Bar C, Silva J, Cohen I, Galbo PM Jr, Liu H, Yu X, Jin J, Koseki H, D'Orazio JA, Zheng D, Ezhkova E. Li MY, et al. Among authors: jin j. Dev Cell. 2021 Sep 27;56(18):2547-2561.e8. doi: 10.1016/j.devcel.2021.08.006. Epub 2021 Sep 1. Dev Cell. 2021. PMID: 34473941 Free PMC article.

9

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models.

Yu X, Li D, Kottur J, Shen Y, Kim HS, Park KS, Tsai YH, Gong W, Wang J, Suzuki K, Parker J, Herring L, Kaniskan HÜ, Cai L, Jain R, Liu J, Aggarwal AK, Wang GG, Jin J. Yu X, et al. Among authors: jin j. Sci Transl Med. 2021 Sep 29;13(613):eabj1578. doi: 10.1126/scitranslmed.abj1578. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586829 Free PMC article.

10

Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders.

Yu X, Xu J, Xie L, Wang L, Shen Y, Cahuzac KM, Chen X, Liu J, Parsons RE, Jin J. Yu X, et al. Among authors: jin j. J Med Chem. 2021 Dec 23;64(24):18054-18081. doi: 10.1021/acs.jmedchem.1c01476. Epub 2021 Dec 2. J Med Chem. 2021. PMID: 34855399 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

12,459 results

Search Page