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Page 1
Developmental Deconvolution for Classification of Cancer Origin.
Moiso E, Farahani A, Marble HD, Hendricks A, Mildrum S, Levine S, Lennerz JK, Garg S. Moiso E, et al. Among authors: lennerz jk. Cancer Discov. 2022 Nov 2;12(11):2566-2585. doi: 10.1158/2159-8290.CD-21-1443. Cancer Discov. 2022. PMID: 36041084 Free PMC article.
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
Gainor JF, Dardaei L, Yoda S, Friboulet L, Leshchiner I, Katayama R, Dagogo-Jack I, Gadgeel S, Schultz K, Singh M, Chin E, Parks M, Lee D, DiCecca RH, Lockerman E, Huynh T, Logan J, Ritterhouse LL, Le LP, Muniappan A, Digumarthy S, Channick C, Keyes C, Getz G, Dias-Santagata D, Heist RS, Lennerz J, Sequist LV, Benes CH, Iafrate AJ, Mino-Kenudson M, Engelman JA, Shaw AT. Gainor JF, et al. Cancer Discov. 2016 Oct;6(10):1118-1133. doi: 10.1158/2159-8290.CD-16-0596. Epub 2016 Jul 18. Cancer Discov. 2016. PMID: 27432227 Free PMC article.
Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer.
Yoda S, Lin JJ, Lawrence MS, Burke BJ, Friboulet L, Langenbucher A, Dardaei L, Prutisto-Chang K, Dagogo-Jack I, Timofeevski S, Hubbeling H, Gainor JF, Ferris LA, Riley AK, Kattermann KE, Timonina D, Heist RS, Iafrate AJ, Benes CH, Lennerz JK, Mino-Kenudson M, Engelman JA, Johnson TW, Hata AN, Shaw AT. Yoda S, et al. Among authors: lennerz jk. Cancer Discov. 2018 Jun;8(6):714-729. doi: 10.1158/2159-8290.CD-17-1256. Epub 2018 Apr 12. Cancer Discov. 2018. PMID: 29650534 Free PMC article.
MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer.
Dagogo-Jack I, Yoda S, Lennerz JK, Langenbucher A, Lin JJ, Rooney MM, Prutisto-Chang K, Oh A, Adams NA, Yeap BY, Chin E, Do A, Marble HD, Stevens SE, Digumarthy SR, Saxena A, Nagy RJ, Benes CH, Azzoli CG, Lawrence MS, Gainor JF, Shaw AT, Hata AN. Dagogo-Jack I, et al. Among authors: lennerz jk. Clin Cancer Res. 2020 Jun 1;26(11):2535-2545. doi: 10.1158/1078-0432.CCR-19-3906. Epub 2020 Feb 21. Clin Cancer Res. 2020. PMID: 32086345 Free PMC article.
Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases.
Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, Naxerova K. Reiter JG, et al. Among authors: lennerz jk. Nat Genet. 2020 Jul;52(7):692-700. doi: 10.1038/s41588-020-0633-2. Epub 2020 May 25. Nat Genet. 2020. PMID: 32451459 Free PMC article.
Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK. Miller TE, et al. Among authors: lennerz jk. FASEB J. 2020 Oct;34(10):13877-13884. doi: 10.1096/fj.202001700RR. Epub 2020 Aug 28. FASEB J. 2020. PMID: 32856766 Free PMC article. Clinical Trial.
A Regulatory Science Initiative to Harmonize and Standardize Digital Pathology and Machine Learning Processes to Speed up Clinical Innovation to Patients.
Marble HD, Huang R, Dudgeon SN, Lowe A, Herrmann MD, Blakely S, Leavitt MO, Isaacs M, Hanna MG, Sharma A, Veetil J, Goldberg P, Schmid JH, Lasiter L, Gallas BD, Abels E, Lennerz JK. Marble HD, et al. Among authors: lennerz jk. J Pathol Inform. 2020 Aug 6;11:22. doi: 10.4103/jpi.jpi_27_20. eCollection 2020. J Pathol Inform. 2020. PMID: 33042601 Free PMC article.
A rapid genotyping panel for detection of primary central nervous system lymphoma.
Gupta M, Burns EJ, Georgantas NZ, Thierauf J, Nayyar N, Gordon A, Jones SS, Pisapia M, Sun Y, Burns RP, Velarde J, Jordan JT, Frigault MJ, Nahed BV, Jones PS, Barker FG, Curry WT, Gupta R, Batchelor TT, Romero JM, Brastianos PK, Marble HD, Martinez-Lage M, Tateishi K, Lennerz JK, Dietrich J, Cahill DP, Carter BS, Shankar GM. Gupta M, et al. Among authors: lennerz jk. Blood. 2021 Aug 5;138(5):382-386. doi: 10.1182/blood.2020010137. Blood. 2021. PMID: 33735913 Free PMC article.
Do not sell regulatory science short.
Lennerz JK, Marble HD, Lasiter L, Poste G, Sirintrapun SJ, Salgado R. Lennerz JK, et al. Nat Med. 2021 Apr;27(4):573-574. doi: 10.1038/s41591-021-01298-6. Nat Med. 2021. PMID: 33795868 No abstract available.
Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay.
Anahtar MN, Shaw BM, Slater D, Byrne EH, Botti-Lodovico Y, Adams G, Schaffner SF, Eversley J, McGrath GEG, Gogakos T, Lennerz J, Marble HD, Ritterhouse LL, Batten JM, Georgantas NZ, Pellerin R, Signorelli S, Thierauf J, Kemball M, Happi C, Grant DS, Ndiaye D, Siddle KJ, Mehta SB, Harris JB, Ryan ET, Pierce VM, LaRocque RC, Lemieux JE, Sabeti PC, Rosenberg ES, Branda JA, Turbett SE. Anahtar MN, et al. J Clin Pathol. 2021 Aug;74(8):496-503. doi: 10.1136/jclinpath-2020-207128. Epub 2021 May 28. J Clin Pathol. 2021. PMID: 34049977 Free PMC article.
262 results