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Page 1
Obesity: a perfect storm for carcinogenesis.
Harris BHL, Macaulay VM, Harris DA, Klenerman P, Karpe F, Lord SR, Harris AL, Buffa FM. Harris BHL, et al. Among authors: karpe f. Cancer Metastasis Rev. 2022 Sep;41(3):491-515. doi: 10.1007/s10555-022-10046-2. Epub 2022 Aug 30. Cancer Metastasis Rev. 2022. PMID: 36038791 Free PMC article. Review.
Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.
Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, Sharma A, Bidaut L, Pollak M, Roy PG, Karpe F, James T, English R, Adams RF, Campo L, Ayers L, Snell C, Roxanis I, Frezza C, Fenwick JD, Buffa FM, Harris AL. Lord SR, et al. Among authors: karpe f. Cell Metab. 2018 Nov 6;28(5):679-688.e4. doi: 10.1016/j.cmet.2018.08.021. Epub 2018 Sep 20. Cell Metab. 2018. PMID: 30244975 Free PMC article. Clinical Trial.
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL. Lord SR, et al. Among authors: karpe f. Br J Cancer. 2020 Jan;122(2):258-265. doi: 10.1038/s41416-019-0665-5. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819193 Free PMC article. Clinical Trial.
Adipose tissue: Fat, yet fit.
Vasan SK, Karpe F. Vasan SK, et al. Among authors: karpe f. Nat Rev Endocrinol. 2016 Jul;12(7):375-6. doi: 10.1038/nrendo.2016.77. Epub 2016 May 27. Nat Rev Endocrinol. 2016. PMID: 27230950 No abstract available.
A haemagglutination test for rapid detection of antibodies to SARS-CoV-2.
Townsend A, Rijal P, Xiao J, Tan TK, Huang KA, Schimanski L, Huo J, Gupta N, Rahikainen R, Matthews PC, Crook D, Hoosdally S, Dunachie S, Barnes E, Street T, Conlon CP, Frater J, Arancibia-Cárcamo CV, Rudkin J, Stoesser N, Karpe F, Neville M, Ploeg R, Oliveira M, Roberts DJ, Lamikanra AA, Tsang HP, Bown A, Vipond R, Mentzer AJ, Knight JC, Kwok AJ, Screaton GR, Mongkolsapaya J, Dejnirattisai W, Supasa P, Klenerman P, Dold C, Baillie JK, Moore SC, Openshaw PJM, Semple MG, Turtle LCW, Ainsworth M, Allcock A, Beer S, Bibi S, Skelly D, Stafford L, Jeffrey K, O'Donnell D, Clutterbuck E, Espinosa A, Mendoza M, Georgiou D, Lockett T, Martinez J, Perez E, Gallardo Sanchez V, Scozzafava G, Sobrinodiaz A, Thraves H, Joly E. Townsend A, et al. Among authors: karpe f. Nat Commun. 2021 Mar 29;12(1):1951. doi: 10.1038/s41467-021-22045-y. Nat Commun. 2021. PMID: 33782398 Free PMC article.
PTEN mutations as a cause of constitutive insulin sensitivity and obesity.
Pal A, Barber TM, Van de Bunt M, Rudge SA, Zhang Q, Lachlan KL, Cooper NS, Linden H, Levy JC, Wakelam MJ, Walker L, Karpe F, Gloyn AL. Pal A, et al. Among authors: karpe f. N Engl J Med. 2012 Sep 13;367(11):1002-11. doi: 10.1056/NEJMoa1113966. N Engl J Med. 2012. PMID: 22970944 Free PMC article.
Obesity--On or Off?
Karpe F, Lindgren CM. Karpe F, et al. N Engl J Med. 2016 Apr 14;374(15):1486-8. doi: 10.1056/NEJMcibr1601693. N Engl J Med. 2016. PMID: 27074072 Free PMC article. No abstract available.
358 results