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42 results

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Page 1
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, Smitheman KN, Ott HM, Pappalardi MB, Allen KE, Chen SB, Della Pietra A 3rd, Dul E, Hughes AM, Gilbert SA, Thrall SH, Tummino PJ, Kruger RG, Brandt M, Schwartz B, Creasy CL. McCabe MT, et al. Among authors: thrall sh. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2989-94. doi: 10.1073/pnas.1116418109. Epub 2012 Feb 8. Proc Natl Acad Sci U S A. 2012. PMID: 22323599 Free PMC article.
A simple assay for detection of small-molecule redox activity.
Lor LA, Schneck J, McNulty DE, Diaz E, Brandt M, Thrall SH, Schwartz B. Lor LA, et al. J Biomol Screen. 2007 Sep;12(6):881-90. doi: 10.1177/1087057107304113. Epub 2007 Jun 19. J Biomol Screen. 2007. PMID: 17579124
Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.
Diaz E, Machutta CA, Chen S, Jiang Y, Nixon C, Hofmann G, Key D, Sweitzer S, Patel M, Wu Z, Creasy CL, Kruger RG, LaFrance L, Verma SK, Pappalardi MB, Le B, Van Aller GS, McCabe MT, Tummino PJ, Pope AJ, Thrall SH, Schwartz B, Brandt M. Diaz E, et al. Among authors: thrall sh. J Biomol Screen. 2012 Dec;17(10):1279-92. doi: 10.1177/1087057112453765. Epub 2012 Aug 17. J Biomol Screen. 2012. PMID: 22904200
A high-throughput screen for endothelial lipase using HDL as substrate.
Keller PM, Rust T, Murphy DJ, Matico R, Trill JJ, Krawiec JA, Jurewicz A, Jaye M, Harpel M, Thrall S, Schwartz B. Keller PM, et al. Among authors: thrall s. J Biomol Screen. 2008 Jul;13(6):468-75. doi: 10.1177/1087057108319738. Epub 2008 Jun 19. J Biomol Screen. 2008. PMID: 18566479
Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.
Schneck JL, Briand J, Chen S, Lehr R, McDevitt P, Zhao B, Smallwood A, Concha N, Oza K, Kirkpatrick R, Yan K, Villa JP, Meek TD, Thrall SH. Schneck JL, et al. Among authors: thrall sh. Biochemistry. 2010 Aug 24;49(33):7151-63. doi: 10.1021/bi100824v. Biochemistry. 2010. PMID: 20597513
A high-throughput screen measuring ubiquitination of p53 by human mdm2.
Murray MF, Jurewicz AJ, Martin JD, Ho TF, Zhang H, Johanson KO, Kirkpatrick RB, Ma J, Lor LA, Thrall SH, Schwartz B. Murray MF, et al. J Biomol Screen. 2007 Dec;12(8):1050-8. doi: 10.1177/1087057107308556. Epub 2007 Nov 7. J Biomol Screen. 2007. PMID: 17989425
Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Totoritis R, Duraiswami C, Taylor AN, Kerrigan JJ, Campobasso N, Smith KJ, Ward P, King BW, Murrayz-Thompson M, Jones AD, Van Aller GS, Aubart KM, Zalacain M, Thrall SH, Meek TD, Schwartz B. Totoritis R, et al. Among authors: thrall sh. Biochemistry. 2011 Aug 9;50(31):6642-54. doi: 10.1021/bi200655g. Biochemistry. 2011. PMID: 21711014
42 results