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Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation.
Lu X, Yang H, Li Q, Chen Y, Li Q, Zhou Y, Feng F, Liu W, Guo Q, Sun H. Lu X, et al. Among authors: feng f. Bioorg Chem. 2019 Apr;85:117-127. doi: 10.1016/j.bioorg.2018.12.023. Epub 2018 Dec 21. Bioorg Chem. 2019. PMID: 30605885
Degradation of proteins by PROTACs and other strategies.
Wang Y, Jiang X, Feng F, Liu W, Sun H. Wang Y, et al. Among authors: feng f. Acta Pharm Sin B. 2020 Feb;10(2):207-238. doi: 10.1016/j.apsb.2019.08.001. Epub 2019 Aug 13. Acta Pharm Sin B. 2020. PMID: 32082969 Free PMC article. Review.
Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
Liu Y, He S, Chen Y, Liu Y, Feng F, Liu W, Guo Q, Zhao L, Sun H. Liu Y, et al. Among authors: feng f. J Med Chem. 2020 Oct 22;63(20):11305-11329. doi: 10.1021/acs.jmedchem.9b02138. Epub 2020 Jun 10. J Med Chem. 2020. PMID: 32463235 Review.
3,599 results