Wong ILK - Search Results

1

Localization of Epigenetic Markers in Leishmania Chromatin.

McDonald JR, Jensen BC, Sur A, Wong ILK, Beverley SM, Myler PJ. McDonald JR, et al. Among authors: wong ilk. Pathogens. 2022 Aug 18;11(8):930. doi: 10.3390/pathogens11080930. Pathogens. 2022. PMID: 36015053 Free PMC article.

2

Kinetoplastid-specific histone variant functions are conserved in Leishmania major.

Anderson BA, Wong IL, Baugh L, Ramasamy G, Myler PJ, Beverley SM. Anderson BA, et al. Mol Biochem Parasitol. 2013 Oct;191(2):53-7. doi: 10.1016/j.molbiopara.2013.09.005. Epub 2013 Sep 27. Mol Biochem Parasitol. 2013. PMID: 24080031 Free PMC article.

3

Identification of Binding Sites in the Nucleotide-Binding Domain of P-Glycoprotein for a Potent and Nontoxic Modulator, the Amine-Containing Monomeric Flavonoid FM04.

Liu Z, Wong ILK, Sang J, Liu F, Yan CSW, Kan JWY, Chan TH, Chow LMC. Liu Z, et al. Among authors: wong ilk. J Med Chem. 2023 May 11;66(9):6160-6183. doi: 10.1021/acs.jmedchem.2c02005. Epub 2023 Apr 25. J Med Chem. 2023. PMID: 37098275

4

In Vivo Reversal of P-Glycoprotein-Mediated Drug Resistance in a Breast Cancer Xenograft and in Leukemia Models Using a Novel, Potent, and Nontoxic Epicatechin EC31.

Sun W, Wong ILK, Law HK, Su X, Chan TCF, Sun G, Yang X, Wang X, Chan TH, Wan S, Chow LMC. Sun W, et al. Among authors: wong ilk. Int J Mol Sci. 2023 Feb 22;24(5):4377. doi: 10.3390/ijms24054377. Int J Mol Sci. 2023. PMID: 36901808 Free PMC article.

5

Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel.

Kan JWY, Yan CSW, Wong ILK, Su X, Liu Z, Chan TH, Chow LMC. Kan JWY, et al. Among authors: wong ilk. Int J Mol Sci. 2022 Dec 4;23(23):15299. doi: 10.3390/ijms232315299. Int J Mol Sci. 2022. PMID: 36499627 Free PMC article.

6

Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)₂, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP/ABCG2).

Chong TC, Wong ILK, Cui J, Law MC, Zhu X, Hu X, Kan JWY, Yan CSW, Chan TH, Chow LMC. Chong TC, et al. Among authors: wong ilk. Int J Mol Sci. 2022 Oct 31;23(21):13261. doi: 10.3390/ijms232113261. Int J Mol Sci. 2022. PMID: 36362047 Free PMC article.

7

Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2).

Wong ILK, Zhu X, Chan KF, Liu Z, Chan CF, Chow TS, Chong TC, Law MC, Cui J, Chow LMC, Chan TH. Wong ILK, et al. J Med Chem. 2021 Oct 14;64(19):14311-14331. doi: 10.1021/acs.jmedchem.1c00779. Epub 2021 Oct 4. J Med Chem. 2021. PMID: 34606270

8

Synthesis and evaluation of stereoisomers of methylated catechin and epigallocatechin derivatives on modulating P-glycoprotein-mediated multidrug resistance in cancers.

Wong ILK, Wang XK, Liu Z, Sun W, Li FX, Wang BC, Li P, Wan SB, Chow LMC. Wong ILK, et al. Eur J Med Chem. 2021 Dec 15;226:113795. doi: 10.1016/j.ejmech.2021.113795. Epub 2021 Sep 1. Eur J Med Chem. 2021. PMID: 34597896

9

Amine-Linked Flavonoids as Agents Against Cutaneous Leishmaniasis.

Chan CF, Liu Z, Wong ILK, Zhao X, Yang Z, Zheng J, Lee MM, Chan MK, Chan TH, Chow LMC. Chan CF, et al. Among authors: wong ilk. Antimicrob Agents Chemother. 2023 May 1;65(5):e02165-20. doi: 10.1128/AAC.02165-20. Epub 2021 Mar 8. Antimicrob Agents Chemother. 2023. PMID: 33685890 Free PMC article.

10

Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo.

Li P, He Y, Chen T, Choy KY, Chow TS, Wong ILK, Yang X, Sun W, Su X, Chan TH, Chow LMC. Li P, et al. Among authors: wong ilk. Mol Cancer Ther. 2021 Jan;20(1):76-84. doi: 10.1158/1535-7163.MCT-20-0130. Epub 2020 Dec 2. Mol Cancer Ther. 2021. PMID: 33268570

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