Gruzman A - Search Results

1

4-Phenylbutyric Acid (4-PBA) Derivatives Prevent SOD1 Amyloid Aggregation In Vitro with No Effect on Disease Progression in SOD1-ALS Mice.

Alfahel L, Argueti-Ostrovsky S, Barel S, Ali Saleh M, Kahn J, Azoulay-Ginsburg S, Rothstein A, Ebbinghaus S, Gruzman A, Israelson A. Alfahel L, et al. Among authors: gruzman a. Int J Mol Sci. 2022 Aug 20;23(16):9403. doi: 10.3390/ijms23169403. Int J Mol Sci. 2022. PMID: 36012668 Free PMC article.

2

Carbonic anhydrase I is recognized by an SOD1 antibody upon biotinylation of human spinal cord extracts.

Liu J, Akhavan A, Lu M, Gruzman A, Lingappa VR, An J, Bowser R. Liu J, et al. Among authors: gruzman a. Int J Mol Sci. 2010 Oct 20;11(10):4051-62. doi: 10.3390/ijms11104051. Int J Mol Sci. 2010. PMID: 21152319 Free PMC article.

3

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

Getter T, Zaks I, Barhum Y, Ben-Zur T, Böselt S, Gregoire S, Viskind O, Shani T, Gottlieb H, Green O, Shubely M, Senderowitz H, Israelson A, Kwon I, Petri S, Offen D, Gruzman A. Getter T, et al. Among authors: gruzman a. ChemMedChem. 2015 May;10(5):850-61. doi: 10.1002/cmdc.201500045. Epub 2015 Mar 13. ChemMedChem. 2015. PMID: 25772747

4

Nrf2 Activation by SK-119 Attenuates Oxidative Stress, UVB, and LPS-Induced Damage.

Kahremany S, Babaev I, Gvirtz R, Ogen-Stern N, Azoulay-Ginsburg S, Senderowitz H, Cohen G, Gruzman A. Kahremany S, et al. Among authors: gruzman a. Skin Pharmacol Physiol. 2019;32(4):173-181. doi: 10.1159/000499432. Epub 2019 May 10. Skin Pharmacol Physiol. 2019. PMID: 31079103

5

A Lipophilic 4-Phenylbutyric Acid Derivative That Prevents Aggregation and Retention of Misfolded Proteins.

Azoulay-Ginsburg S, Trobiani L, Setini A, Favaloro FL, Giorda E, Jacob A, Hauschner H, Levy L, Cestra G, De Jaco A, Gruzman A. Azoulay-Ginsburg S, et al. Among authors: gruzman a. Chemistry. 2020 Feb 6;26(8):1834-1845. doi: 10.1002/chem.201904292. Epub 2020 Jan 27. Chemistry. 2020. PMID: 31773792

6

Advances in Understanding the Initial Steps of Pruritoceptive Itch: How the Itch Hits the Switch.

Kahremany S, Hofmann L, Gruzman A, Cohen G. Kahremany S, et al. Among authors: gruzman a. Int J Mol Sci. 2020 Jul 10;21(14):4883. doi: 10.3390/ijms21144883. Int J Mol Sci. 2020. PMID: 32664385 Free PMC article. Review.

7

Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model.

Azoulay-Ginsburg S, Di Salvio M, Weitman M, Afri M, Ribeiro S, Ebbinghaus S, Cestra G, Gruzman A. Azoulay-Ginsburg S, et al. Among authors: gruzman a. Pharmacol Rep. 2021 Apr;73(2):536-550. doi: 10.1007/s43440-021-00226-2. Epub 2021 Mar 4. Pharmacol Rep. 2021. PMID: 33661518

8

Investigation of the Membrane Fluidity Regulation of Fatty Acid Intracellular Distribution by Fluorescence Lifetime Imaging of Novel Polarity Sensitive Fluorescent Derivatives.

Bianchetti G, Azoulay-Ginsburg S, Keshet-Levy NY, Malka A, Zilber S, Korshin EE, Sasson S, De Spirito M, Gruzman A, Maulucci G. Bianchetti G, et al. Among authors: gruzman a. Int J Mol Sci. 2021 Mar 18;22(6):3106. doi: 10.3390/ijms22063106. Int J Mol Sci. 2021. PMID: 33803648 Free PMC article.

9

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

Gruzman A, Wood WL, Alpert E, Prasad MD, Miller RG, Rothstein JD, Bowser R, Hamilton R, Wood TD, Cleveland DW, Lingappa VR, Liu J. Gruzman A, et al. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12524-9. doi: 10.1073/pnas.0705044104. Epub 2007 Jul 16. Proc Natl Acad Sci U S A. 2007. PMID: 17636119 Free PMC article.

10

Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation.

Daniel B, Green O, Viskind O, Gruzman A. Daniel B, et al. Among authors: gruzman a. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Sep;14(5-6):434-43. doi: 10.3109/21678421.2013.808226. Epub 2013 Jul 8. Amyotroph Lateral Scler Frontotemporal Degener. 2013. PMID: 23834207

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